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Induced pluripotent stem cells: opportunities and challenges

Somatic cells have been reprogrammed into pluripotent stem cells by introducing a combination of several transcription factors, such as Oct3/4, Sox2, Klf4 and c-Myc. Induced pluripotent stem (iPS) cells from a patient's somatic cells could be a useful source for drug discovery and cell transpla...

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Detalhes bibliográficos
Main Authors: Okita, Keisuke, Yamanaka, Shinya
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130417/
https://ncbi.nlm.nih.gov/pubmed/21727125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2011.0016
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