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Induced Pluripotent Stem Cells: Challenges and Opportunities for Cancer Immunotherapy

Despite recent advances in cancer treatment over the past 30 years, therapeutic options remain limited and do not always offer a cure for malignancy. Given that tumor-associated antigens (TAA) are, by definition, self-proteins, the need to productively engage autoreactive T cells remains at the hear...

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Autori principali: Sachamitr, Patty, Hackett, Simon, Fairchild, Paul Jonathan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029000/
https://ncbi.nlm.nih.gov/pubmed/24860566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00176
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