DISTINCT ROUTES OF LINEAGE DEVELOPMENT RESHAPE THE HUMAN BLOOD HIERARCHY ACROSS ONTOGENY

Classically, blood arises from stem cells through a series of oligopotent progenitors that become increasingly restricted to unipotent progenitors, each slotted into a hierarchical layer based on their differentiation potential. The presence of oligopotent cells is critical to the standard model of...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Notta, Faiyaz, Zandi, Sasan, Takayama, Naoya, Dobson, Stephanie, Gan, Olga I, Wilson, Gavin, Kaufmann, Kerstin B, McLeod, Jessica, Laurenti, Elisa, Dunant, Cyrille F, McPherson, John D, Stein, Lincoln D, Dror, Yigal, Dick, John E
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816201/
https://ncbi.nlm.nih.gov/pubmed/26541609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab2116
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