Retroviral transduction of TLS-ERG initiates a leukemogenic program in normal human hematopoietic cells

Por Pereira, Daniel S., Dorrell, Craig, Ito, Caryn Y., Gan, Olga I., Murdoch, Barbara, Rao, Veena N., Zou, Jian-Ping, Reddy, E. Shyam P., Dick, John E.
Publicado em 1998

Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cells

Por Wagenblast, Elvin, Azkanaz, Maria, Smith, Sabrina A., Shakib, Lorien, McLeod, Jessica L., Krivdova, Gabriela, Araújo, Joana, Shultz, Leonard D., Gan, Olga I., Dick, John E., Lechman, Eric R.
Publicado no Nat Commun (2019)

DISTINCT ROUTES OF LINEAGE DEVELOPMENT RESHAPE THE HUMAN BLOOD HIERARCHY ACROSS ONTOGENY

Por Notta, Faiyaz, Zandi, Sasan, Takayama, Naoya, Dobson, Stephanie, Gan, Olga I, Wilson, Gavin, Kaufmann, Kerstin B, McLeod, Jessica, Laurenti, Elisa, Dunant, Cyrille F, McPherson, John D, Stein, Lincoln D, Dror, Yigal, Dick, John E
Publicado no Science (2015)

SMYD2 lysine methyltransferase regulates leukemia cell growth and regeneration after genotoxic stress

Por Zipin-Roitman, Adi, Aqaqe, Nasma, Yassin, Muhammad, Biechonski, Shahar, Amar, Mariam, van Delft, Mark F., Gan, Olga I., McDermott, Sean P., Buzina, Alla, Ketela, Troy, Shlush, Liran, Xie, Stephanie, Voisin, Veronique, Moffat, Jason, Minden, Mark D., Dick, John E., Milyavsky, Michael
Publicado no Oncotarget (2017)

Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal

Por Xie, Stephanie Z., Garcia-Prat, Laura, Voisin, Veronique, Ferrari, Robin, Gan, Olga I., Wagenblast, Elvin, Kaufmann, Kerstin B., Zeng, Andy G.X., Takayanagi, Shin-ichiro, Patel, Ishita, Lee, Esther K., Jargstorf, Joseph, Holmes, Gareth, Romm, Guy, Pan, Kristele, Shoong, Michelle, Vedi, Aditi, Luberto, Chiara, Minden, Mark D., Bader, Gary D., Laurenti, Elisa, Dick, John E.
Publicado no Cell Stem Cell (2019)

Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors

Por Wojtowicz, Edyta E., Lechman, Eric R., Hermans, Karin G., Schoof, Erwin M., Wienholds, Erno, Isserlin, Ruth, van Veelen, Peter A., Broekhuis, Mathilde J.C., Janssen, George M.C., Trotman-Grant, Aaron, Dobson, Stephanie M., Krivdova, Gabriela, Elzinga, Jantje, Kennedy, James, Gan, Olga I., Sinha, Ankit, Ignatchenko, Vladimir, Kislinger, Thomas, Dethmers-Ausema, Bertien, Weersing, Ellen, Alemdehy, Mir Farshid, de Looper, Hans W.J., Bader, Gary D., Ritsema, Martha, Erkeland, Stefan J., Bystrykh, Leonid V., Dick, John E., de Haan, Gerald
Publicado no Cell Stem Cell (2016)

Sphingosine-1-Phosphate Receptor 3 Potentiates Inflammatory Programs in Normal and Leukemia Stem Cells to Promote Differentiation

Por Xie, Stephanie Z., Kaufmann, Kerstin B., Wang, Weijia, Chan-Seng-Yue, Michelle, Gan, Olga I., Laurenti, Elisa, Garcia-Prat, Laura, Takayanagi, Shin-ichiro, Ng, Stanley W.K., Xu, ChangJiang, Zeng, Andy G.X., Jin, Liqing, McLeod, Jessica, Wagenblast, Elvin, Mitchell, Amanda, Kennedy, James A., Liu, Qiang, Boutzen, Héléna, Kleinau, Melissa, Jargstorf, Joseph, Holmes, Gareth, Zhang, Yang, Voisin, Veronique, Bader, Gary D., Wang, Jean C.Y., Hannun, Yusuf A., Luberto, Chiara, Schroeder, Timm, Minden, Mark D., Dick, John E.
Publicado no Blood Cancer Discov (2020)

Relapse fated latent diagnosis subclones in acute B lineage leukaemia are drug tolerant and possess distinct metabolic programs

Por Dobson, Stephanie M., García-Prat, Laura, Vanner, Robert J., Wintersinger, Jeffrey, Waanders, Esmé, Gu, Zhaohui, McLeod, Jessica, Gan, Olga I., Grandal, Ildiko, Payne-Turner, Debbie, Edmonson, Michael N., Ma, Xiaotu, Fan, Yiping, Voisin, Veronique, Chan-Seng-Yue, Michelle, Xie, Stephanie Z., Hosseini, Mohsen, Abelson, Sagi, Gupta, Pankaj, Rusch, Michael, Shao, Ying, Olsen, Scott R., Neale, Geoffrey, Chan, Steven M., Bader, Gary, Easton, John, Guidos, Cynthia J., Danska, Jayne S., Zhang, Jinghui, Minden, Mark D., Morris, Quaid, Mullighan, Charles G., Dick, John E.
Publicado no Cancer Discov (2020)

Inherited myeloproliferative neoplasm risk impacts hematopoietic stem cells

Por Bao, Erik L., Nandakumar, Satish K., Liao, Xiaotian, Bick, Alexander G., Karjalainen, Juha, Tabaka, Marcin, Gan, Olga I., Havulinna, Aki, Kiiskinen, Tuomo, Lareau, Caleb A., de Lapuente Portilla, Aitzkoa Lopez, Li, Bo, Emdin, Connor, Codd, Veryan, Nelson, Christopher P., Walker, Christopher J., Churchhouse, Claire, de la Chapelle, Albert, Klein, Daryl E., Nilsson, Björn, Wilson, Peter W.F., Cho, Kelly, Pyarajan, Saiju, Gaziano, J. Michael, Samani, Nilesh J., Regev, Aviv, Palotie, Aarno, Neale, Benjamin M., Dick, John E., Natarajan, Pradeep, O’Donnell, Christopher J., Daly, Mark J., Milyavsky, Michael, Kathiresan, Sekar, Sankaran, Vijay G.
Publicado no Nature (2020)