In The Blood: Connecting Variant to Function In Human Hematopoiesis

Por Nandakumar, Satish K., Liao, Xiaotian, Sankaran, Vijay G.
Publicado no Trends Genet (2020)

Advances in Understanding Erythropoiesis: Evolving Perspectives

Por Nandakumar, Satish K., Ulirsch, Jacob C., Sankaran, Vijay G.
Publicado no Br J Haematol (2016)

Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits

Por Ulirsch, Jacob C., Nandakumar, Satish K., Wang, Li, Giani, Felix C., Zhang, Xiaolan, Rogov, Peter, Melnikov, Alexandre, McDonel, Patrick, Do, Ron, Mikkelsen, Tarjei S., Sankaran, Vijay G.
Publicado no Cell (2016)

Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis

Por Ludwig, Leif S., Lareau, Caleb A., Bao, Erik L., Nandakumar, Satish K., Muus, Christoph, Ulirsch, Jacob C., Chowdhary, Kaitavjeet, Buenrostro, Jason D., Mohandas, Narla, An, Xiuli, Aryee, Martin J., Regev, Aviv, Sankaran, Vijay G.
Publicado no Cell Rep (2019)

Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis

Por Nandakumar, Satish K, McFarland, Sean K, Mateyka, Laura M, Lareau, Caleb A, Ulirsch, Jacob C, Ludwig, Leif S, Agarwal, Gaurav, Engreitz, Jesse M, Przychodzen, Bartlomiej, McConkey, Marie, Cowley, Glenn S, Doench, John G, Maciejewski, Jaroslaw P, Ebert, Benjamin L, Root, David E, Sankaran, Vijay G
Publicado no eLife (2019)

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

Por Guo, Michael H., Nandakumar, Satish K., Ulirsch, Jacob C., Zekavat, Seyedeh M., Buenrostro, Jason D., Natarajan, Pradeep, Salem, Rany M., Chiarle, Roberto, Mitt, Mario, Kals, Mart, Pärn, Kalle, Fischer, Krista, Milani, Lili, Mägi, Reedik, Palta, Priit, Gabriel, Stacey B., Metspalu, Andres, Lander, Eric S., Kathiresan, Sekar, Hirschhorn, Joel N., Esko, Tõnu, Sankaran, Vijay G.
Publicado no Proc Natl Acad Sci U S A (2017)

Infantile Myelofibrosis and Myeloproliferation with CDC42 Dysfunction

Por Verboon, Jeffrey M., Mahmut, Dilnar, Kim, Ah Ram, Nakamura, Mitsutoshi, Abdulhay, Nour J., Nandakumar, Satish K., Gupta, Namrata, Akie, Thomas E., Geddis, Amy E., Manes, Becky, Kapp, Meghan E., Hofmann, Inga, Gabriel, Stacey B., Klein, Daryl E., Williams, David A., Frangoul, Haydar A., Parkhurst, Susan M., Crane, Genevieve M., Cantor, Alan B., Sankaran, Vijay G.
Publicado no J Clin Immunol (2020)

Common variants in signaling transcription factor binding sites drive phenotypic variability in red blood cell traits

Por Choudhuri, Avik, Trompouki, Eirini, Abraham, Brian J., Colli, Leandro M., Kock, Kian Hong, Mallard, William, Yang, Min–Lee, Vinjamur, Divya S., Ghamari, Alireza, Sporrij, Audrey, Hoi, Karen, Hummel, Barbara, Boatman, Sonja, Chan, Victoria, Tseng, Sierra, Nandakumar, Satish K., Yang, Song, Lichtig, Asher, Superdock, Michael, Grimes, Seraj N., Bowman, Teresa V., Zhou, Yi, Takahashi, Shinichiro, Joehanes, Roby, Cantor, Alan B., Bauer, Daniel E., Ganesh, Santhi K., Rinn, John, Albert, Paul S., Bulyk, Martha L., Chanock, Stephen J., Young, Richard A., Zon, Leonard I.
Publicado no Nat Genet (2020)

Inherited myeloproliferative neoplasm risk impacts hematopoietic stem cells

Por Bao, Erik L., Nandakumar, Satish K., Liao, Xiaotian, Bick, Alexander G., Karjalainen, Juha, Tabaka, Marcin, Gan, Olga I., Havulinna, Aki, Kiiskinen, Tuomo, Lareau, Caleb A., de Lapuente Portilla, Aitzkoa Lopez, Li, Bo, Emdin, Connor, Codd, Veryan, Nelson, Christopher P., Walker, Christopher J., Churchhouse, Claire, de la Chapelle, Albert, Klein, Daryl E., Nilsson, Björn, Wilson, Peter W.F., Cho, Kelly, Pyarajan, Saiju, Gaziano, J. Michael, Samani, Nilesh J., Regev, Aviv, Palotie, Aarno, Neale, Benjamin M., Dick, John E., Natarajan, Pradeep, O’Donnell, Christopher J., Daly, Mark J., Milyavsky, Michael, Kathiresan, Sekar, Sankaran, Vijay G.
Publicado no Nature (2020)

Inherited Causes of Clonal Hematopoiesis in 97,691 TOPMed Whole Genomes

Por Bick, Alexander G., Weinstock, Joshua S., Nandakumar, Satish K., Fulco, Charles P., Bao, Erik L., Zekavat, Seyedeh M., Szeto, Mindy D., Liao, Xiaotian, Leventhal, Matthew J., Nasser, Joseph, Chang, Kyle, Laurie, Cecelia, Burugula, Bala Bharathi, Gibson, Christopher J., Lin, Amy E., Taub, Margaret A., Aguet, Francois, Ardlie, Kristin, Mitchell, Braxton D., Barnes, Kathleen C., Moscati, Arden, Fornage, Myriam, Redline, Susan, Psaty, Bruce M., Silverman, Edwin K., Weiss, Scott T., Palmer, Nicholette D., Vasan, Ramachandran S., Burchard, Esteban G., Kardia, Sharon L. R., He, Jiang, Kaplan, Robert C., Smith, Nicholas L., Arnett, Donna K., Schwartz, David A., Correa, Adolfo, de Andrade, Mariza, Guo, Xiuqing, Konkle, Barbara A., Custer, Brian, Peralta, Juan M., Gui, Hongsheng, Meyers, Deborah A., McGarvey, Stephen T., Chen, Ida Yii-Der., Shoemaker, M. Benjamin, Peyser, Patricia A., Broome, Jai G., Gogarten, Stephanie M., Wang, Fei Fei, Wong, Quenna, Montasser, May E., Daya, Michelle, Kenny, Eimear E., North, Kari E., Launer, Lenore J., Cade, Brian E., Bis, Joshua C., Cho, Michael H., Lasky-Su, Jessica, Bowden, Donald W., Cupples, L. Adrienne., Mak, Angel C., Becker, Lewis C., Smith, Jennifer A., Kelly, Tanika N., Aslibekyan, Stella, Heckbert, Susan R., Tiwari, Hemant K., Yang, Ivana V., Heit, John A., Lubitz, Steven, Johnsen, Jill M., Curran, Joanne E., Wenzel, Sally E., Weeks, Daniel E., Rao, Dabeeru C., Darbar, Dawood, Moon, Jee-Young, Tracy, Russell P., Buth, Erin J., Rafaels, Nicholas, Loos, Ruth J.F., Durda, Peter, Liu, Yongmei, Hou, Lifang, Lee, Jiwon, Kachroo, Priyadarshini, Freedman, Barry I., Levy, Daniel, Bielak, Lawrence F., Hixson, James E., Floyd, James S., Whitsel, Eric A., Ellinor, Patrick T., Irvin, Marguerite R., Fingerlin, Tasha E., Raffield, Laura M., Armasu, Sebastian M., Wheeler, Marsha M., Sabino, Ester C., Blangero, John, Williams, L. Keoki, Levy, Bruce D., Huey-Herng Sheu, Wayne, Roden, Dan M., Boerwinkle, Eric, Manson, JoAnn E., Mathias, Rasika A., Desai, Pinkal, Taylor, Kent D., Johnson, Andrew D., Auer, Paul L., Kooperberg, Charles, Laurie, Cathy C., Blackwell, Thomas W., Smith, Albert V., Zhao, Hongyu, Lange, Ethan, Lange, Leslie, Rich, Stephen S., Rotter, Jerome I., Wilson, James G., Scheet, Paul, Kitzman, Jacob O., Lander, Eric S., Engreitz, Jesse M., Ebert, Benjamin L., Reiner, Alexander P., Jaiswal, Siddhartha, Abecasis, Gonçalo, Sankaran, Vijay G., Kathiresan, Sekar, Natarajan, Pradeep
Publicado no Nature (2020)