Emerging Cellular and Gene Therapies for Congenital Anemias

Por Ludwig, Leif S., Khajuria, Rajiv K., Sankaran, Vijay G.
Publicado no Am J Med Genet C Semin Med Genet (2016)

Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells

Por Polansky, Julia K., Schreiber, Lisa, Thelemann, Christoph, Ludwig, Leif, Krüger, Melanie, Baumgrass, Ria, Cording, Sascha, Floess, Stefan, Hamann, Alf, Huehn, Jochen
Publicado em 2010

Genome-wide association study follow-up identifies cyclin A2 as a regulator of the transition through cytokinesis during terminal erythropoiesis

Por Ludwig, Leif S., Cho, Hyunjii, Wakabayashi, Aoi, Eng, Jennifer C., Ulirsch, Jacob C., Fleming, Mark D., Lodish, Harvey F., Sankaran, Vijay G.
Publicado no Am J Hematol (2015)

Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders

Por Wakabayashi, Aoi, Ulirsch, Jacob C., Ludwig, Leif S., Fiorini, Claudia, Yasuda, Makiko, Choudhuri, Avik, McDonel, Patrick, Zon, Leonard I., Sankaran, Vijay G.
Publicado no Proc Natl Acad Sci U S A (2016)

X-linked macrocytic dyserythropoietic anemia in females with an ALAS2 mutation

Por Sankaran, Vijay G., Ulirsch, Jacob C., Tchaikovskii, Vassili, Ludwig, Leif S., Wakabayashi, Aoi, Kadirvel, Senkottuvelan, Lindsley, R. Coleman, Bejar, Rafael, Shi, Jiahai, Lovitch, Scott B., Bishop, David F., Steensma, David P.
Publicado no J Clin Invest (2015)

Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number

Por Sankaran, Vijay G., Ludwig, Leif S., Sicinska, Ewa, Xu, Jian, Bauer, Daniel E., Eng, Jennifer C., Patterson, Heide Christine, Metcalf, Ryan A., Natkunam, Yasodha, Orkin, Stuart H., Sicinski, Piotr, Lander, Eric S., Lodish, Harvey F.
Publicado em 2012

Altered translation of GATA1 in Diamond-Blackfan anemia

Por Ludwig, Leif S., Gazda, Hanna T., Eng, Jennifer C., Eichhorn, Stephen W., Thiru, Prathapan, Ghazvinian, Roxanne, George, Tracy I., Gotlib, Jason R., Beggs, Alan H., Sieff, Colin A., Lodish, Harvey F., Lander, Eric S., Sankaran, Vijay G.
Publicado em 2014

Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells

Por Giani, Felix C., Fiorini, Claudia, Wakabayashi, Aoi, Ludwig, Leif S., Salem, Rany M., Jobaliya, Chintan D., Regan, Stephanie N., Ulirsch, Jacob C., Liang, Ge, Steinberg-Shemer, Orna, Guo, Michael H., Esko, Tõnu, Tong, Wei, Brugnara, Carlo, Hirschhorn, Joel N., Weiss, Mitchell J., Zon, Leonard I., Chou, Stella T., French, Deborah L., Musunuru, Kiran, Sankaran, Vijay G.
Publicado no Cell Stem Cell (2015)