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Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders
Whole-exome sequencing has been incredibly successful in identifying causal genetic variants and has revealed a number of novel genes associated with blood and other diseases. One limitation of this approach is that it overlooks mutations in noncoding regulatory elements. Furthermore, the mechanisms...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4843446/ https://ncbi.nlm.nih.gov/pubmed/27044088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521754113 |
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