Inducible Gata1 suppression expands megakaryocyte-erythroid progenitors from embryonic stem cells

Transfusion of donor-derived platelets is commonly used for thrombocytopenia, which results from a variety of clinical conditions and relies on a constant donor supply due to the limited shelf life of these cells. Embryonic stem (ES) and induced pluripotent stem (iPS) cells represent a potential sou...

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Vydáno v:J Clin Invest
Hlavní autoři: Noh, Ji-Yoon, Gandre-Babbe, Shilpa, Wang, Yuhuan, Hayes, Vincent, Yao, Yu, Gadue, Paul, Sullivan, Spencer K., Chou, Stella T., Machlus, Kellie R., Italiano, Joseph E., Kyba, Michael, Finkelstein, David, Ulirsch, Jacob C., Sankaran, Vijay G., French, Deborah L., Poncz, Mortimer, Weiss, Mitchell J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2015
Témata:
Brief Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497743/
https://ncbi.nlm.nih.gov/pubmed/25961454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77670
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