Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells

Human (h) induced pluripotent stem cells (iPSCs) are a potentially abundant source of blood cells, but how best to select iPSC clones suitable for this purpose from among the many clones that can be simultaneously established from an identical source is not clear. Using an in vitro culture system yi...

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Autori principali: Takayama, Naoya, Nishimura, Satoshi, Nakamura, Sou, Shimizu, Takafumi, Ohnishi, Ryoko, Endo, Hiroshi, Yamaguchi, Tomoyuki, Otsu, Makoto, Nishimura, Ken, Nakanishi, Mahito, Sawaguchi, Akira, Nagai, Ryozo, Takahashi, Kazutoshi, Yamanaka, Shinya, Nakauchi, Hiromitsu, Eto, Koji
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005234/
https://ncbi.nlm.nih.gov/pubmed/21098095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100844
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