Another small molecule in the oncometabolite mix: L-2-Hydroxyglutarate in kidney cancer

Por Shim, Eun-Hee, Sudarshan, Sunil
Publicado no Oncoscience (2015)

Genetics of renal cancer: focus on MTOR

Por Ghosh, Arindam P., Sudarshan, Sunil
Publicado no Aging (Albany NY) (2016)

Strangulated Richter’s Umbilical Hernia - A Case Report

Por Martis, John J. S., Rajeshwara, K. V., Shridhar, M. Kalpana, Janardhanan, Deepak, Sudarshan, Sunil
Publicado em 2011

Feasibility and Outcomes of Repeat Partial Nephrectomy

Por Johnson, Aaron, Sudarshan, Sunil, Liu, Jack, Linehan, W. Marston, Pinto, Peter A., Bratslavsky, Gennady
Publicado em 2008

The Oncometabolite Fumarate Promotes Pseudohypoxia Through Noncanonical Activation of NF-κB Signaling

Por Shanmugasundaram, Karthigayan, Nayak, Bijaya, Shim, Eun-Hee, Livi, Carolina B., Block, Karen, Sudarshan, Sunil
Publicado em 2014

Repeat Partial Nephrectomy on the Solitary Kidney: Surgical, Functional, and Oncologic Outcomes

Por Liu, Nick W., Khurana, Kiranpreet, Sudarshan, Sunil, Pinto, Peter A., Linehan, W. Marston, Bratslavsky, Gennady
Publicado em 2010

PI3K regulation of the SKP-2/p27 axis through mTORC2

Por Shanmugasundaram, Karthigayan, Block, Karen, Nayak, Bijaya K., Livi, Carolina B., Venkatachalam, Manjeri A., Sudarshan, Sunil
Publicado em 2012

Increasing reactive oxygen species as a therapeutic approach to treat hereditary leiomyomatosis and renal cell carcinoma

Por Sourbier, Carole, Valera-Romero, Vladimir, Giubellino, Alessio, Yang, Youfeng, Sudarshan, Sunil, Neckers, Len, Linehan, W Marston
Publicado em 2010

Metastatic prostate cancer to an ischiorectal fossa lymph node identified on multiparametric magnetic resonance imaging

Por Fang, Andrew M., Galgano, Samuel J., Gordetsky, Jennifer B., Sudarshan, Sunil, McDonald, Andrew M., Rais-Bahrami, Soroush
Publicado no Urol Ann (2020)

Metabolism of Kidney Cancer: From the Lab to Clinical Practice

Por Sudarshan, Sunil, Karam, Jose, Brugarolas, James, Thompson, Houston, Uzzo, Robert, Rini, Brian, Margulis, Vitaly, Patard, Jean-Jacques, Escudier, Bernard, Linehan, W. Marston
Publicado em 2012

The proto-oncometabolite fumarate binds glutathione to amplify ROS dependent signaling

Por Sullivan, Lucas B., Garcia-Martinez, Eva, Nguyen, Hien, Mullen, Andrew R., Dufour, Eric, Sudarshan, Sunil, Licht, Jonathan D., Deberardinis, Ralph J., Chandel, Navdeep S.
Publicado em 2013

Point mutations of the mTOR-RHEB pathway in renal cell carcinoma

Por Ghosh, Arindam P., Marshall, Christopher B., Coric, Tatjana, Shim, Eun-hee, Kirkman, Richard, Ballestas, Mary E., Ikura, Mitsuhiko, Bjornsti, Mary-Ann, Sudarshan, Sunil
Publicado no Oncotarget (2015)

Nox4 Mediates Renal Cell Carcinoma Cell Invasion through Hypoxia-Induced Interleukin 6- and 8- Production

Por Fitzgerald, John P., Nayak, Bijaya, Shanmugasundaram, Karthigayan, Friedrichs, William, Sudarshan, Sunil, Eid, Assaad A., DeNapoli, Thomas, Parekh, Dipen J., Gorin, Yves, Block, Karen
Publicado em 2012

Kinomic profiling identifies focal adhesion kinase 1 as a therapeutic target in advanced clear cell renal cell carcinoma

Por Ghosh, Arindam P., Willey, Christopher D., Anderson, Joshua C., Welaya, Karim, Chen, Dongquan, Mehta, Amitkumar, Ghatalia, Pooja, Madan, Ankit, Naik, Gurudatta, Sudarshan, Sunil, Sonpavde, Guru
Publicado no Oncotarget (2017)

Integrative Epigenetic and Gene Expression Analysis of Renal Tumor Progression to Metastasis

Por Nam, Hye-Young, Chandrashekar, Darshan S., Kundu, Anirban, Shelar, Sandeep, Kho, Eun-Young, Sonpavde, Guru, Naik, Gurudatta, Ghatalia, Pooja, Livi, Carolina B., Varambally, Sooryanarayana, Sudarshan, Sunil
Publicado no Mol Cancer Res (2018)

Reduced Expression of Fumarate Hydratase in Clear Cell Renal Cancer Mediates HIF-2α Accumulation and Promotes Migration and Invasion

Por Sudarshan, Sunil, Shanmugasundaram, Karthigayan, Naylor, Susan L., Lin, Shu, Livi, Carolina B., O'Neill, Christine F., Parekh, Dipen J., Yeh, I-Tien, Sun, Lu-Zhe, Block, Karen
Publicado em 2011

14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylation

Por Kundu, Anirban, Shelar, Sandeep, Ghosh, Arindam P., Ballestas, Mary, Kirkman, Richard, Nam, Hyeyoung, Brinkley, Garrett J., Karki, Suman, Mobley, James A., Bae, Sejong, Varambally, Sooryanarayana, Sudarshan, Sunil
Publicado no J Biol Chem (2020)

Stabilization of HIF-2alpha through redox regulation of mTORC2 activation and initiation of mRNA translation

Por Nayak, Bijaya K., Feliers, Denis, Sudarshan, Sunil, Friedrichs, William E., Day, Robert T., New, David D., Fitzgerald, John P., Eid, Assaad, DeNapoli, Thomas, Parekh, Dipen J., Gorin, Yves, Block, Karen
Publicado em 2012

PRDM16 suppresses HIF-targeted gene expression in kidney cancer

Por Kundu, Anirban, Nam, Hyeyoung, Shelar, Sandeep, Chandrashekar, Darshan S., Brinkley, Garrett, Karki, Suman, Mitchell, Tanecia, Livi, Carolina B., Buckhaults, Phillip, Kirkman, Richard, Tang, Yawen, Rowe, Glenn C., Wei, Shi, Varambally, Sooryanarayana, Sudarshan, Sunil
Publicado no J Exp Med (2020)

High Throughput Kinomic Profiling of Human Clear Cell Renal Cell Carcinoma Identifies Kinase Activity Dependent Molecular Subtypes

Por Anderson, Joshua C., Willey, Christopher D., Mehta, Amitkumar, Welaya, Karim, Chen, Dongquan, Duarte, Christine W., Ghatalia, Pooja, Arafat, Waleed, Madan, Ankit, Sudarshan, Sunil, Naik, Gurudatta, Grizzle, William E., Choueiri, Toni K., Sonpavde, Guru
Publicado no PLoS One (2015)