14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylation

Ten-eleven translocation-2 (TET2) is a member of the methylcytosine dioxygenase family of enzymes and has been implicated in cancer and aging because of its role as a global epigenetic modifier. TET2 has a large N-terminal domain and a catalytic C-terminal region. Previous reports have demonstrated...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kundu, Anirban, Shelar, Sandeep, Ghosh, Arindam P., Ballestas, Mary, Kirkman, Richard, Nam, Hyeyoung, Brinkley, Garrett J., Karki, Suman, Mobley, James A., Bae, Sejong, Varambally, Sooryanarayana, Sudarshan, Sunil
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008385/
https://ncbi.nlm.nih.gov/pubmed/31901078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011089
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