Low Ten-eleven-translocation 2 (TET2) transcript level is independent of TET2 mutation in patients with myeloid neoplasms

BACKGROUND: New sequencing technologies have enabled the identification of mutations in Ten-eleven-translocation 2 (TET2), an enzyme that catalyzes the conversion of 5-methylcytosine into 5-hydroxymethylcytosine (5-hmC) in myeloid neoplasms. We have recently identified reduced TET2 mRNA expression i...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Diagn Pathol
Autori principali: Scopim-Ribeiro, Renata, Machado-Neto, João Agostinho, de Melo Campos, Paula, Niemann, Fernanda Soares, Lorand-Metze, Irene, Costa, Fernando Ferreira, Olalla Saad, Sara Teresinha, Traina, Fabiola
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Short Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793581/
https://ncbi.nlm.nih.gov/pubmed/26984174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-016-0476-4
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