PGC1α suppresses kidney cancer progression by inhibiting collagen-induced SNAIL expression

The transcriptional events that promote invasive and metastatic phenotypes in renal cell carcinoma (RCC) remain poorly understood. Here we report that the decreased expression of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC1α) and the increased expression of several gen...

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Gepubliceerd in:Matrix Biol
Hoofdauteurs: Nam, Hyeyoung, Kundu, Anirban, Brinkley, Garrett J., Chandrashekar, Darshan S., Kirkman, Richard L., Chakravarthi, Balabhadrapatruni V. S. K., Orlandella, Rachael M., Norian, Lyse A., Sonpavde, Guru, Ghatalia, Pooja, Fei, Fei, Wei, Shi, Varambally, Sooryanarayana, Sudarshan, Sunil
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712461/
https://ncbi.nlm.nih.gov/pubmed/31982456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2020.01.001
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