Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition

per Jiang, Lei, Xiao, Ling, Sugiura, Hidekazu, Huang, Xiumei, Ali, Aktar, Kuro-o, Makoto, Deberardinis, Ralph J., Boothman, David A.
Publicat a Oncogene (2014)

Glutathione Depletion, Pentose Phosphate Pathway Activation, and Hemolysis in Erythrocytes Protecting Cancer Cells from Vitamin C-induced Oxidative Stress

per Zhang, Zhuzhen Z., Lee, Eunice E., Sudderth, Jessica, Yue, Yangbo, Zia, Ayesha, Glass, Donald, Deberardinis, Ralph J., Wang, Richard C.
Publicat a J Biol Chem (2016)

The proto-oncometabolite fumarate binds glutathione to amplify ROS dependent signaling

per Sullivan, Lucas B., Garcia-Martinez, Eva, Nguyen, Hien, Mullen, Andrew R., Dufour, Eric, Sudarshan, Sunil, Licht, Jonathan D., Deberardinis, Ralph J., Chandel, Navdeep S.
Publicat 2013

Loss of a Negative Regulator of mTORC1 Induces Aerobic Glycolysis and Altered Fiber Composition in Skeletal Muscle

per Dutchak, Paul A., Estill-Terpack, Sandi J., Plec, Abigail A., Zhao, Xiaozheng, Yang, Chendong, Chen, Jun, Ko, Bookyung, Deberardinis, Ralph J., Yu, Yonghao, Tu, Benjamin P.
Publicat a Cell Rep (2018)

A role for the mitochondrial pyruvate carrier as a repressor of the Warburg Effect and colon cancer cell growth

per Schell, John C., Olson, Kristofor A., Jiang, Lei, Hawkins, Amy J., Van Vranken, Jonathan G., Xie, Jianxin, Egnatchik, Robert A., Earl, Espen G., Deberardinis, Ralph J., Rutter, Jared
Publicat a Mol Cell (2014)

Does Tumor FDG-PET-Avidity Represent Enhanced Glycolytic Metabolism in Non-Small Cell Lung Cancer?

per Kernstine, Kemp H., Faubert, Brandon, Do, Quyen N., Rogers, Thomas J., Hensley, Christopher T., Cai, Ling, Torrealba, Jose, Oliver, Dwight, Waschmann, Jason W., Lenkinski, Robert E., Malloy, Craig R., Deberardinis, Ralph J.
Publicat a Ann Thorac Surg (2019)

Using a novel NQO1 bioactivatable drug, beta-lapachone (ARQ761), to enhance chemotherapeutic effects by metabolic modulation in Pancreatic Cancer

per Beg, Muhammad Shaalan, Huang, Xiumei, Silvers, Molly A., Gerber, David E., Bolluyt, Joyce, Sarode, Venetia, Fattah, Farjana, Deberardinis, Ralph J., Merritt, Matthew E., Xie, Xian-Jin, Leff, Richard, Laheru, Daniel, Boothman, David A.
Publicat a J Surg Oncol (2017)

The G protein-coupled taste receptor T1R1/T1R3 regulates mTORC1 and autophagy

per Wauson, Eric M., Zaganjor, Elma, Lee, A-Young, Guerra, Marcy L., Ghosh, Anwesha B., Bookout, Angie L., Chambers, Chris P., Jivan, Arif, McGlynn, Kathleen, Hutchison, Michele R., Deberardinis, Ralph J., Cobb, Melanie H.
Publicat 2012

Systematic Identification of Molecular Subtype-Selective Vulnerabilities in Non Small Cell Lung Cancer

per Kim, Hyun Seok, Mendiratta, Saurabh, Kim, Jiyeon, Pecot, Chad Victor, Larsen, Jill E., Zubovych, Iryna, Seo, Bo Yeun, Kim, Jimi, Eskiocak, Banu, Chung, Hannah, McMillan, Elizabeth, Wu, Sherry, De Brabander, Jef, Komurov, Kakajan, Toombs, Jason E., Wei, Shuguang, Peyton, Michael, Williams, Noelle, Gazdar, Adi F., Posner, Bruce A., Brekken, Rolf, Sood, Anil K., Deberardinis, Ralph J., Roth, Michael G., Minna, John D., White, Michael A.
Publicat 2013

Chemistry-first approach for nomination of personalized treatment in lung cancer

per McMillan, Elizabeth A., Ryu, Myung-Jeom, Diep, Caroline H., Mendiratta, Saurabh, Clemenceau, Jean R., Vaden, Rachel M., Kim, Ju-Hwa, Motoyaji, Takashi, Covington, Kyle R., Peyton, Michael, Huffman, Kenneth, Wu, Xiaofeng, Girard, Luc, Sung, Yeojin, Chen, Pei-Hsaun, Mallipeddi, Prema L., Lee, Joo Young, Hanson, Jordan, Voruganti, Sukesh, Yu, Yunku, Park, Sunho, Sudderth, Jessica, DeSevo, Christopher, Muzny, Donna M., Doddapaneni, HarshaVardhan, Gazdar, Adi, Gibbs, Richard A., Hwang, Tae-Hyun, Heymach, John V., Wistuba, Ignacio, Coombes, Kevin R., Williams, Noelle S., Wheeler, David A., MacMillan, John B., Deberardinis, Ralph J., Roth, Michael G., Posner, Bruce A., Minna, John D., Kim, Hyun Seok, White, Michael A.
Publicat a Cell (2018)