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A role for the mitochondrial pyruvate carrier as a repressor of the Warburg Effect and colon cancer cell growth
Cancer cells are typically subject to profound metabolic alterations, including the Warburg effect wherein cancer cells oxidize a decreased fraction of the pyruvate generated from glycolysis. We show herein that the mitochondrial pyruvate carrier (MPC), composed of the products of the MPC1 and MPC2...
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| 出版年: | Mol Cell |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4268416/ https://ncbi.nlm.nih.gov/pubmed/25458841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.09.026 |
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