Molecular Mechanisms and the Role of Saturated Fatty Acids in the Progression of Non-Alcoholic Fatty Liver Disease

מאת Leamy, Alexandra K., Egnatchik, Robert A., Young, Jamey D.
יצא לאור 2012

Microfluidic mixing for sperm activation and motility analysis of pearl Danio zebrafish

מאת Park, Daniel S., Egnatchik, Robert A., Bordelon, Hali, Tiersch, Terrence R., Monroe, W. Todd
יצא לאור 2012

Palmitate-induced Activation of Mitochondrial Metabolism Promotes Oxidative Stress and Apoptosis in H4IIEC3 Rat Hepatocytes

מאת Egnatchik, Robert A., Leamy, Alexandra K., Noguchi, Yasushi, Shiota, Masakazu, Young, Jamey D.
יצא לאור 2013

ER calcium release promotes mitochondrial dysfunction and hepatic cell lipotoxicity in response to palmitate overload

מאת Egnatchik, Robert A., Leamy, Alexandra K., Jacobson, David A., Shiota, Masakazu, Young, Jamey D.
יצא לאור 2014

Glutamate–oxaloacetate transaminase activity promotes palmitate lipotoxicity in rat hepatocytes by enhancing anaplerosis and citric acid cycle flux

מאת Egnatchik, Robert A., Leamy, Alexandra K., Sacco, Sarah A., Cheah, Yi Ern, Shiota, Masakazu, Young, Jamey D.
הוצא לאור ב J Biol Chem (2019)

Enhanced synthesis of saturated phospholipids is associated with ER stress and lipotoxicity in palmitate treated hepatic cells

מאת Leamy, Alexandra K., Egnatchik, Robert A., Shiota, Masakazu, Ivanova, Pavlina T., Myers, David S., Brown, H. Alex, Young, Jamey D.
יצא לאור 2014

Knockdown of Triglyceride Synthesis Does Not Enhance Palmitate Lipotoxicity or Prevent Oleate-Mediated Rescue in Rat Hepatocytes

מאת Leamy, Alexandra K., Hasenour, Clinton M., Egnatchik, Robert A., Trenary, Irina A., Yao, Conghui, Patti, Gary J., Shiota, Masakazu, Young, Jamey D.
הוצא לאור ב Biochim Biophys Acta (2016)

LKB1 deficiency enhances sensitivity to energetic stress induced by erlotinib treatment in non-small cell lung cancer (NSCLC) cells

מאת Whang, Young Mi, Park, Serk In, Trenary, Irina A., Egnatchik, Robert A., Fessel, Joshua P., Kaufman, Jacob M., Carbone, David P., Young, Jamey D.
הוצא לאור ב Oncogene (2015)

A role for the mitochondrial pyruvate carrier as a repressor of the Warburg Effect and colon cancer cell growth

מאת Schell, John C., Olson, Kristofor A., Jiang, Lei, Hawkins, Amy J., Van Vranken, Jonathan G., Xie, Jianxin, Egnatchik, Robert A., Earl, Espen G., Deberardinis, Ralph J., Rutter, Jared
הוצא לאור ב Mol Cell (2014)

The NQO1 bioactivatable drug, β-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism

מאת Silvers, Molly A., Deja, Stanislaw, Singh, Naveen, Egnatchik, Robert A., Sudderth, Jessica, Luo, Xiuquan, Beg, Muhammad S., Burgess, Shawn C., DeBerardinis, Ralph J., Boothman, David A., Merritt, Matthew E.
הוצא לאור ב J Biol Chem (2017)

Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells

מאת Rajagopalan, Kartik N., Egnatchik, Robert A., Calvaruso, Maria A., Wasti, Ajla T., Padanad, Mahesh S., Boroughs, Lindsey K., Ko, Bookyung, Hensley, Christopher T., Acar, Melih, Hu, Zeping, Jiang, Lei, Pascual, Juan M., Scaglioni, Pier Paolo, DeBerardinis, Ralph J.
הוצא לאור ב Cancer Metab (2015)

Dysfunctional BMPR2 signaling drives an abnormal endothelial requirement for glutamine in pulmonary arterial hypertension

מאת Egnatchik, Robert A., Brittain, Evan L., Shah, Amy T., Fares, Wassim H., Ford, H. James, Monahan, Ken, Kang, Christie J., Kocurek, Emily G., Zhu, Shijun, Luong, Thong, Nguyen, Thuy T., Hysinger, Erik, Austin, Eric D., Skala, Melissa C., Young, Jamey D., Roberts, L. Jackson, Hemnes, Anna R., West, James, Fessel, Joshua P.
הוצא לאור ב Pulm Circ (2017)