Hepatic glucose sensing: does flux matter?

por Shiota, Masakazu, Magnuson, Mark A.
Publicado 2008

Palmitate-induced Activation of Mitochondrial Metabolism Promotes Oxidative Stress and Apoptosis in H4IIEC3 Rat Hepatocytes

por Egnatchik, Robert A., Leamy, Alexandra K., Noguchi, Yasushi, Shiota, Masakazu, Young, Jamey D.
Publicado 2013

Phosphoenolpyruvate Carboxykinase Is Necessary for the Integration of Hepatic Energy Metabolism

por She, Pengxiang, Shiota, Masakazu, Shelton, Kathy D., Chalkley, Roger, Postic, Catherine, Magnuson, Mark A.
Publicado 2000

ER calcium release promotes mitochondrial dysfunction and hepatic cell lipotoxicity in response to palmitate overload

por Egnatchik, Robert A., Leamy, Alexandra K., Jacobson, David A., Shiota, Masakazu, Young, Jamey D.
Publicado 2014

Identification of the Toxicity Pathways Associated With Thioacetamide-Induced Injuries in Rat Liver and Kidney

por Schyman, Patric, Printz, Richard L., Estes, Shanea K., Boyd, Kelli L., Shiota, Masakazu, Wallqvist, Anders
Publicado en Front Pharmacol (2018)

The Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 is a Pseudogene in Guinea Pigs Potentially Contributing to Low Guinea Pig Islet Zinc Content

por Syring, Kristen E., Bosma, Karin J., Oeser, James K., Shiota, Masakazu, O’Brien, Richard M.
Publicado en J Mol Evol (2018)

Assessing Chemical-Induced Liver Injury In Vivo From In Vitro Gene Expression Data in the Rat: The Case of Thioacetamide Toxicity

por Schyman, Patric, Printz, Richard L., Estes, Shanea K., O’Brien, Tracy P., Shiota, Masakazu, Wallqvist, Anders
Publicado en Front Genet (2019)

Concordance between Thioacetamide-Induced Liver Injury in Rat and Human In Vitro Gene Expression Data

por Schyman, Patric, Printz, Richard L., Estes, Shanea K., O’Brien, Tracy P., Shiota, Masakazu, Wallqvist, Anders
Publicado en Int J Mol Sci (2020)

A physiological increase in the hepatic glycogen level does not affect the response of net hepatic glucose uptake to insulin

por Winnick, Jason J., An, Zhibo, Moore, Mary Courtney, Ramnanan, Christopher J., Farmer, Ben, Shiota, Masakazu, Cherrington, Alan D.
Publicado 2009

Priming Effect of a Morning Meal on Hepatic Glucose Disposition Later in the Day

por Moore, Mary Courtney, Smith, Marta S., Farmer, Ben, Kraft, Guillaume, Shiota, Masakazu, Williams, Phillip E., Cherrington, Alan D.
Publicado en Diabetes (2017)

Effect of adrenal medullectomy on metabolic responses to chronic intermittent hypoxia in the frequently sampled intravenous glucose tolerance test

por Shin, Mi-Kyung, Han, Woobum, Joo, Hoon, Bevans-Fonti, Shannon, Shiota, Masakazu, Stefanovski, Darko, Polotsky, Vsevolod Y.
Publicado en J Appl Physiol (1985) (2017)

Glutamate–oxaloacetate transaminase activity promotes palmitate lipotoxicity in rat hepatocytes by enhancing anaplerosis and citric acid cycle flux

por Egnatchik, Robert A., Leamy, Alexandra K., Sacco, Sarah A., Cheah, Yi Ern, Shiota, Masakazu, Young, Jamey D.
Publicado en J Biol Chem (2019)

Enhanced synthesis of saturated phospholipids is associated with ER stress and lipotoxicity in palmitate treated hepatic cells

por Leamy, Alexandra K., Egnatchik, Robert A., Shiota, Masakazu, Ivanova, Pavlina T., Myers, David S., Brown, H. Alex, Young, Jamey D.
Publicado 2014

Defective Glycogenesis Contributes Toward the Inability to Suppress Hepatic Glucose Production in Response to Hyperglycemia and Hyperinsulinemia in Zucker Diabetic Fatty Rats

por Torres, Tracy P., Fujimoto, Yuka, Donahue, E.P., Printz, Richard L., Houseknecht, Karen L., Treadway, Judith L., Shiota, Masakazu
Publicado 2011

Morning Hyperinsulinemia Primes the Liver for Glucose Uptake and Glycogen Storage Later in the Day

por Moore, Mary Courtney, Smith, Marta S., Farmer, Ben, Coate, Katie C., Kraft, Guillaume, Shiota, Masakazu, Williams, Phillip E., Cherrington, Alan D.
Publicado en Diabetes (2018)

Restoration of Hepatic Glucokinase Expression Corrects Hepatic Glucose Flux and Normalizes Plasma Glucose in Zucker Diabetic Fatty Rats

por Torres, Tracy P., Catlin, ReEtta L., Chan, Robert, Fujimoto, Yuka, Sasaki, Noriyasu, Printz, Richard L., Newgard, Christopher B., Shiota, Masakazu
Publicado 2009

Impact of a Glycogen Phosphorylase Inhibitor and Metformin on Basal and Glucagon-Stimulated Hepatic Glucose Flux in Conscious Dogs

por Torres, Tracy P., Sasaki, Noriyasu, Donahue, E. Patrick, Lacy, Brooks, Printz, Richard L., Cherrington, Alan D., Treadway, Judith L., Shiota, Masakazu
Publicado 2011

Hepatic Glucose Metabolism in Late Pregnancy: Normal Versus High-Fat and -Fructose Diet

por Coate, Katie C., Smith, Marta S., Shiota, Masakazu, Irimia, Jose M., Roach, Peter J., Farmer, Ben, Williams, Phillip E., Moore, Mary Courtney
Publicado 2013

Chronic overeating impairs hepatic glucose uptake and disposition

por Coate, Katie C., Kraft, Guillaume, Shiota, Masakazu, Smith, Marta S., Farmer, Ben, Neal, Doss W., Williams, Phil, Cherrington, Alan D., Moore, Mary Courtney
Publicado en Am J Physiol Endocrinol Metab (2015)

Knockdown of Triglyceride Synthesis Does Not Enhance Palmitate Lipotoxicity or Prevent Oleate-Mediated Rescue in Rat Hepatocytes

por Leamy, Alexandra K., Hasenour, Clinton M., Egnatchik, Robert A., Trenary, Irina A., Yao, Conghui, Patti, Gary J., Shiota, Masakazu, Young, Jamey D.
Publicado en Biochim Biophys Acta (2016)