Concordance between Thioacetamide-Induced Liver Injury in Rat and Human In Vitro Gene Expression Data

The immense resources required and the ethical concerns for animal-based toxicological studies have driven the development of in vitro and in silico approaches. Recently, we validated our approach in which the expression of a set of genes is uniquely associated with an organ-injury phenotype (injury...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Schyman, Patric, Printz, Richard L., Estes, Shanea K., O’Brien, Tracy P., Shiota, Masakazu, Wallqvist, Anders
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312807/
https://ncbi.nlm.nih.gov/pubmed/32512829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21114017
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