Toxicant-Induced Metabolic Alterations in Lipid and Amino Acid Pathways Are Predictive of Acute Liver Toxicity in Rats

Liver disease and disorders associated with aberrant hepatocyte metabolism can be initiated via drug and environmental toxicant exposures. In this study, we tested the hypothesis that gene and metabolic profiling can reveal commonalities in liver response to different toxicants and provide the capab...

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Pubblicato in:Int J Mol Sci
Autori principali: Pannala, Venkat R., Estes, Shanea K., Rahim, Mohsin, Trenary, Irina, O’Brien, Tracy P., Shiota, Chiyo, Printz, Richard L., Reifman, Jaques, Shiota, Masakazu, Young, Jamey D., Wallqvist, Anders
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7663358/
https://ncbi.nlm.nih.gov/pubmed/33158035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218250
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