Toxicant-Induced Metabolic Alterations in Lipid and Amino Acid Pathways Are Predictive of Acute Liver Toxicity in Rats

Liver disease and disorders associated with aberrant hepatocyte metabolism can be initiated via drug and environmental toxicant exposures. In this study, we tested the hypothesis that gene and metabolic profiling can reveal commonalities in liver response to different toxicants and provide the capab...

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Udgivet i:Int J Mol Sci
Main Authors: Pannala, Venkat R., Estes, Shanea K., Rahim, Mohsin, Trenary, Irina, O’Brien, Tracy P., Shiota, Chiyo, Printz, Richard L., Reifman, Jaques, Shiota, Masakazu, Young, Jamey D., Wallqvist, Anders
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7663358/
https://ncbi.nlm.nih.gov/pubmed/33158035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218250
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