Network Modeling of Liver Metabolism to Predict Plasma Metabolite Changes During Short-Term Fasting in the Laboratory Rat

The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fatty-acid regulation, and detoxify ammonia—is susceptible to injuries induced by drugs and toxic substances. Although plasma metabolite profiles are increasingly investigated for their potential to det...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Vinnakota, Kalyan C., Pannala, Venkat R., Wall, Martha L., Rahim, Mohsin, Estes, Shanea K., Trenary, Irina, O’Brien, Tracy P., Printz, Richard L., Reifman, Jaques, Shiota, Masakazu, Young, Jamey D., Wallqvist, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405515/
https://ncbi.nlm.nih.gov/pubmed/30881311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00161
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