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Metabolic network-based predictions of toxicant-induced metabolite changes in the laboratory rat

In order to provide timely treatment for organ damage initiated by therapeutic drugs or exposure to environmental toxicants, we first need to identify markers that provide an early diagnosis of potential adverse effects before permanent damage occurs. Specifically, the liver, as a primary organ pron...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Pannala, Venkat R., Wall, Martha L., Estes, Shanea K., Trenary, Irina, O’Brien, Tracy P., Printz, Richard L., Vinnakota, Kalyan C., Reifman, Jaques, Shiota, Masakazu, Young, Jamey D., Wallqvist, Anders
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076258/
https://ncbi.nlm.nih.gov/pubmed/30076366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30149-7
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