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Metabolic network-based predictions of toxicant-induced metabolite changes in the laboratory rat

In order to provide timely treatment for organ damage initiated by therapeutic drugs or exposure to environmental toxicants, we first need to identify markers that provide an early diagnosis of potential adverse effects before permanent damage occurs. Specifically, the liver, as a primary organ pron...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pannala, Venkat R., Wall, Martha L., Estes, Shanea K., Trenary, Irina, O’Brien, Tracy P., Printz, Richard L., Vinnakota, Kalyan C., Reifman, Jaques, Shiota, Masakazu, Young, Jamey D., Wallqvist, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076258/
https://ncbi.nlm.nih.gov/pubmed/30076366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30149-7
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