Network Modeling of Liver Metabolism to Predict Plasma Metabolite Changes During Short-Term Fasting in the Laboratory Rat

The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fatty-acid regulation, and detoxify ammonia—is susceptible to injuries induced by drugs and toxic substances. Although plasma metabolite profiles are increasingly investigated for their potential to det...

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Dettagli Bibliografici
Pubblicato in:Front Physiol
Autori principali: Vinnakota, Kalyan C., Pannala, Venkat R., Wall, Martha L., Rahim, Mohsin, Estes, Shanea K., Trenary, Irina, O’Brien, Tracy P., Printz, Richard L., Reifman, Jaques, Shiota, Masakazu, Young, Jamey D., Wallqvist, Anders
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405515/
https://ncbi.nlm.nih.gov/pubmed/30881311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00161
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