Foxa2 and MafA Regulate Islet-specific Glucose-6-Phosphatase Catalytic Subunit-Related Protein (IGRP/G6PC2) Gene Expression

por Martin, Cyrus C., Flemming, Brian P., Wang, Yingda, Oeser, James K., O’Brien, Richard M.
Publicado 2008

The Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 is a Pseudogene in Guinea Pigs Potentially Contributing to Low Guinea Pig Islet Zinc Content

por Syring, Kristen E., Bosma, Karin J., Oeser, James K., Shiota, Masakazu, O’Brien, Richard M.
Publicado en J Mol Evol (2018)

Upstream stimulatory factor (USF) and neurogenic differentiation/beta-cell E box transactivator 2 (NeuroD/BETA2) contribute to islet-specific glucose-6-phosphatase catalytic-subuni...

por Martin, Cyrus C, Svitek, Christina A, Oeser, James K, Henderson, Eva, Stein, Roland, O'Brien, Richard M
Publicado 2003

Functional Analysis of Mouse G6pc1 Mutations Using a Novel In Situ Assay for Glucose-6-Phosphatase Activity and the Effect of Mutations in Conserved Human G6PC1/G6PC2 Amino Acids o...

por Boortz, Kayla A., Syring, Kristen E., Pound, Lynley D., Wang, Yingda, Oeser, James K., O’Brien, Richard M.
Publicado en PLoS One (2016)

Sequence Variation Between the Mouse and Human Glucose-6-Phosphatase Catalytic Subunit Gene Promoters Results in Differential Activation by Peroxisome Proliferator Activator Recept...

por Schilling, Marcia M., Oeser, James K., Chandy, Joshua K., Flemming, Brian P., Allen, Shelley R., O’Brien, Richard M.
Publicado 2008

G6PC2 confers protection against hypoglycemia upon ketogenic diet feeding and prolonged fasting

por Bosma, Karin J., Rahim, Mohsin, Oeser, James K., McGuinness, Owen P., Young, Jamey D., O'Brien, Richard M.
Publicado en Mol Metab (2020)

Hepatocyte nuclear factor-4 alpha mediates the stimulatory effect of peroxisome proliferator-activated receptor gamma co-activator-1 alpha (PGC-1 alpha) on glucose-6-phosphatase ca...

por Boustead, Jared N, Stadelmaier, Beth T, Eeds, Angela M, Wiebe, Peter O, Svitek, Christina A, Oeser, James K, O'Brien, Richard M
Publicado 2003

Insulin and Epidermal Growth Factor Suppress Basal Glucose-6-Phosphatase Catalytic Subunit Gene Transcription Through Overlapping but Distinct Mechanisms

por Onuma, Hiroshi, Oeser, James K., Nelson, Bryce A., Wang, Yingda, Flemming, Brian P., Scheving, Lawrence A., Russell, William E., O’Brien, Richard M.
Publicado 2009

Evidence That Evolution of the Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 Drives Variations in Pancreatic Islet Zinc Content in Multiple Species

por Bosma, Karin J., Syring, Kristen E., Oeser, James K., Lee, Jason D., Benninger, Richard K. P., Pamenter, Matthew E., O’Brien, Richard M.
Publicado en J Mol Evol (2019)

G6PC2 Modulates the Effects of Dexamethasone on Fasting Blood Glucose and Glucose Tolerance

por Boortz, Kayla A., Syring, Kristen E., Lee, Rebecca A., Dai, Chunhua, Oeser, James K., McGuinness, Owen P., Wang, Jen-Chywan, O'Brien, Richard M.
Publicado en Endocrinology (2016)

Characterization of the Human SLC30A8 Promoter and Intronic Enhancer

por Pound, Lynley D., Sarkar, Suparna A., Cauchi, Stéphane, Wang, Yingda, Oeser, James K., Lee, Catherine E., Froguel, Philippe, Hutton, John C., O'Brien1, Richard M.
Publicado 2011

Effects of G6pc2 Deletion on Body Weight and Cholesterol in Mice

por Boortz, Kayla A., Syring, Kristen E., Pound, Lynley D., Mo, Huan, Bastarache, Lisa, Oeser, James K., McGuinness, Owen P., Denny, Joshua C., O’Brien, Richard M.
Publicado en J Mol Endocrinol (2017)

The Pancreatic Islet Beta Cell-Enriched Transcription Factor Pdx-1 Regulates Slc30a8 Gene Transcription Through an Intronic Enhancer

por Pound, Lynley D., Hang, Yan, Sarkar, Suparna A., Wang, Yingda, Milam, Laurel A., Oeser, James K., Printz, Richard L., Lee, Catherine E., Stein, Roland, Hutton, John C., O’Brien, Richard M.
Publicado 2011

G6PC2 Modulates Fasting Blood Glucose In Male Mice in Response to Stress

por Boortz, Kayla A., Syring, Kristen E., Dai, Chunhua, Pound, Lynley D., Oeser, James K., Jacobson, David A., Wang, Jen-Chywan, McGuinness, Owen P., Powers, Alvin C., O'Brien, Richard M.
Publicado en Endocrinology (2016)

Combined Deletion of Slc30a7 and Slc30a8 Unmasks a Critical Role for ZnT8 in Glucose-Stimulated Insulin Secretion

por Syring, Kristen E., Boortz, Kayla A., Oeser, James K., Ustione, Alessandro, Platt, Kenneth A., Shadoan, Melanie K., McGuinness, Owen P., Piston, David W., Powell, David R., O'Brien, Richard M.
Publicado en Endocrinology (2016)

Deletion of the G6pc2 Gene Encoding the Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein Does Not Affect the Progression or Incidence of Type 1 Diabetes in NO...

por Oeser, James K., Parekh, Vrajesh V., Wang, Yingda, Jegadeesh, Naresh K., Sarkar, Suparna A., Wong, Randall, Lee, Catherine E., Pound, Lynley D., Hutton, John C., Van Kaer, Luc, O’Brien, Richard M.
Publicado 2011

G6PC2: A Negative Regulator of Basal Glucose-Stimulated Insulin Secretion

por Pound, Lynley D., Oeser, James K., O’Brien, Tracy P., Wang, Yingda, Faulman, Chandler J., Dadi, Prasanna K., Jacobson, David A., Hutton, John C., McGuinness, Owen P., Shiota, Masakazu, O’Brien, Richard M.
Publicado 2013

Potential Positive and Negative Consequences of ZnT8 Inhibition

por Syring, Kristen E., Bosma, Karin J., Goleva, Slavina B., Singh, Kritika, Oeser, James K., Lopez, Christopher A., Skaar, Eric P., McGuinness, Owen P., Davis, Lea K., Powell, David R., O’Brien, Richard M.
Publicado en J Endocrinol (2020)

Deletion of the Mouse Slc30a8 Gene Encoding Zinc Transporter-8 Results in Impaired Insulin Secretion

por Pound, Lynley D., Sarkar, Suparna, Benninger, Richard K. P., Wang, Yingda, Suwanichkul, Adisak, Shadoan, Melanie K., Printz, Richard L., Oeser, James K., Lee, Catherine E., Piston, David W., McGuinness, Owen P., Hutton, John C., Powell, David R., O’Brien, Richard M.
Publicado 2009

Pancreatic Islet Beta Cell-Specific Deletion of G6pc2 Reduces Fasting Blood Glucose

por Bosma, Karin J., Rahim, Mohsin, Singh, Kritika, Goleva, Slavina B., Wall, Martha L., Xia, Jing, Syring, Kristen E., Oeser, James K., Poffenberger, Greg, McGuinness, Owen P., Means, Anna L., Powers, Alvin C., Li, Wen-hong, Davis, Lea K., Young, Jamey D., O’Brien, Richard M.
Publicado en J Mol Endocrinol (2020)