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Insulin and Epidermal Growth Factor Suppress Basal Glucose-6-Phosphatase Catalytic Subunit Gene Transcription Through Overlapping but Distinct Mechanisms

The glucose-6-phosphatase catalytic subunit (G6Pase) catalyses the final step in the gluconeogenic and glycogenolytic pathways, the hydrolysis of glucose-6-phosphate to glucose. We show here that, in HepG2 hepatoma cells, epidermal growth factor (EGF) inhibits basal mouse G6Pase fusion gene transcri...

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Detalhes bibliográficos
Main Authors: Onuma, Hiroshi, Oeser, James K., Nelson, Bryce A., Wang, Yingda, Flemming, Brian P., Scheving, Lawrence A., Russell, William E., O’Brien, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929524/
https://ncbi.nlm.nih.gov/pubmed/18847435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20080999
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