Sequence Variation Between the Mouse and Human Glucose-6-Phosphatase Catalytic Subunit Gene Promoters Results in Differential Activation by Peroxisome Proliferator Activator Receptor Gamma Coactivator-1α

AIMS/HYPOTHESIS: The glucose-6-phosphatase catalytic subunit (G6PC) plays a key role in hepatic glucose production by catalyzing the final step in gluconeogenesis and glycogenolysis. Peroxisome proliferator activator receptor gamma coactivator-1α (PGC-1α) markedly stimulates mouse G6PC fusion gene e...

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Main Authors: Schilling, Marcia M., Oeser, James K., Chandy, Joshua K., Flemming, Brian P., Allen, Shelley R., O’Brien, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590337/
https://ncbi.nlm.nih.gov/pubmed/18563384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-008-1050-8
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