Pancreatic Islet Beta Cell-Specific Deletion of G6pc2 Reduces Fasting Blood Glucose

The G6PC1, G6PC2 and G6PC3 genes encode distinct glucose-6-phosphatase catalytic subunit (G6PC) isoforms. In mice, germline deletion of G6pc2 lowers fasting blood glucose (FBG) without affecting fasting plasma insulin (FPI) while, in isolated islets, glucose-6-phosphatase activity and glucose cyclin...

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Detaylı Bibliyografya
Yayımlandı:J Mol Endocrinol
Asıl Yazarlar: Bosma, Karin J., Rahim, Mohsin, Singh, Kritika, Goleva, Slavina B., Wall, Martha L., Xia, Jing, Syring, Kristen E., Oeser, James K., Poffenberger, Greg, McGuinness, Owen P., Means, Anna L., Powers, Alvin C., Li, Wen-hong, Davis, Lea K., Young, Jamey D., O’Brien, Richard M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331801/
https://ncbi.nlm.nih.gov/pubmed/32213654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-20-0031
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