Pancreatic β-Cell–specific Ablation of TASK-1 Channels Augments Glucose-stimulated Calcium Entry and Insulin Secretion, Improving Glucose Tolerance

nork Dadi, Prasanna K., Vierra, Nicholas C., Jacobson, David A.
Argitaratua 2014

TASK-1 Potassium Channels Limit Pancreatic α-Cell Calcium Influx and Glucagon Secretion

nork Dadi, Prasanna K., Luo, Brooke, Vierra, Nicholas C., Jacobson, David A.
Argitaratua izan da Mol Endocrinol (2015)

Osteopontin activates the diabetes-associated potassium channel TALK-1 in pancreatic β-cells

nork Dickerson, Matthew T., Vierra, Nicholas C., Milian, Sarah C., Dadi, Prasanna K., Jacobson, David A.
Argitaratua izan da PLoS One (2017)

Dietary bioflavonoids inhibit Escherichia coli ATP synthase in a differential manner

nork Chinnam, Nagababu, Dadi, Prasanna K, Sabri, Shahbaaz A, Ahmad, Mubeen, Kabir, M Anaul, Ahmad, Zulfiqar
Argitaratua 2010

Type 2 Diabetes–Associated K(+) Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose Homeostasis

nork Vierra, Nicholas C., Dadi, Prasanna K., Jeong, Imju, Dickerson, Matthew, Powell, David R., Jacobson, David A.
Argitaratua izan da Diabetes (2015)

Antagonistic epistasis of Hnf4α and FoxO1 metabolic networks through enhancer interactions in β-cell function

nork Kuo, Taiyi, Du, Wen, Miyachi, Yasutaka, Dadi, Prasanna K., Jacobson, David A., Segrè, Daniel, Accili, Domenico
Argitaratua izan da Mol Metab (2021)

Inhibition of Pancreatic β-Cell Ca(2+)/Calmodulin-dependent Protein Kinase II Reduces Glucose-stimulated Calcium Influx and Insulin Secretion, Impairing Glucose Tolerance

nork Dadi, Prasanna K., Vierra, Nicholas C., Ustione, Alessandro, Piston, David W., Colbran, Roger J., Jacobson, David A.
Argitaratua 2014

TALK-1 channels control β cell endoplasmic reticulum Ca(2+) homeostasis

nork Vierra, Nicholas C., Dadi, Prasanna K., Milian, Sarah C., Dickerson, Matthew T., Jordan, Kelli L., Gilon, Patrick, Jacobson, David A.
Argitaratua izan da Sci Signal (2017)

Selective Small Molecule Activators of TREK-2 Channels Stimulate Dorsal Root Ganglion c-Fiber Nociceptor Two-Pore-Domain Potassium Channel Currents and Limit Calcium Influx

nork Dadi, Prasanna K., Vierra, Nicholas C., Days, Emily, Dickerson, Matthew T., Vinson, Paige N., Weaver, C. David, Jacobson, David A
Argitaratua izan da ACS Chem Neurosci (2016)

Cytokine-mediated changes in K(+) channel activity promotes an adaptive Ca(2+) response that sustains β-cell insulin secretion during inflammation

nork Dickerson, Matthew T., Bogart, Avery M., Altman, Molly K., Milian, Sarah C., Jordan, Kelli L., Dadi, Prasanna K., Jacobson, David A.
Argitaratua izan da Sci Rep (2018)

Direct Activation of β-Cell K(ATP) Channels with a Novel Xanthine Derivative

nork Raphemot, Rene, Swale, Daniel R., Dadi, Prasanna K., Jacobson, David A., Cooper, Paige, Wojtovich, Andrew P., Banerjee, Sreedatta, Nichols, Colin G., Denton, Jerod S.
Argitaratua 2014

Activation of FoxM1 Revitalizes the Replicative Potential of Aged β-Cells in Male Mice and Enhances Insulin Secretion

nork Golson, Maria L., Dunn, Jennifer C., Maulis, Matthew F., Dadi, Prasanna K., Osipovich, Anna B., Magnuson, Mark A., Jacobson, David A., Gannon, Maureen
Argitaratua izan da Diabetes (2015)

TALK-1 reduces delta-cell endoplasmic reticulum and cytoplasmic calcium levels limiting somatostatin secretion

nork Vierra, Nicholas C., Dickerson, Matthew T., Jordan, Kelli L., Dadi, Prasanna K., Kadare, Ketaki A., Altman, Molly K., Milian, Sarah C., Jacobson, David A.
Argitaratua izan da Mol Metab (2018)

Tetraspanin-7 regulation of L-type voltage-dependent calcium channels controls pancreatic β-cell insulin secretion

nork Dickerson, Matthew T., Dadi, Prasanna K., Butterworth, Regan B., Nakhe, Arya Y., Graff, Sarah M., Zaborska, Karolina E., Schaub, Charles M., Jacobson, David A.
Argitaratua izan da J Physiol (2020)

Glucose-mediated inhibition of calcium-activated potassium channels limits α-cell calcium influx and glucagon secretion

nork Dickerson, Matthew T., Dadi, Prasanna K., Altman, Molly K., Verlage, Kenneth R., Thorson, Ariel S., Jordan, Kelli L., Vierra, Nicholas C., Amarnath, Gautami, Jacobson, David A.
Argitaratua izan da Am J Physiol Endocrinol Metab (2019)

Chronic β-Cell Depolarization Impairs β-Cell Identity by Disrupting a Network of Ca(2+)-Regulated Genes

nork Stancill, Jennifer S., Cartailler, Jean-Philippe, Clayton, Hannah W., O’Connor, James T., Dickerson, Matthew T., Dadi, Prasanna K., Osipovich, Anna B., Jacobson, David A., Magnuson, Mark A.
Argitaratua izan da Diabetes (2017)

Temporal Transcriptome Analysis Reveals Dynamic Gene Expression Patterns Driving β-Cell Maturation

nork Sanavia, Tiziana, Huang, Chen, Manduchi, Elisabetta, Xu, Yanwen, Dadi, Prasanna K., Potter, Leah A., Jacobson, David A., Di Camillo, Barbara, Magnuson, Mark A., Stoeckert, Christian J., Gu, Guoqiang
Argitaratua izan da Front Cell Dev Biol (2021)

Lactate activation of α-cell K(ATP) channels inhibits glucagon secretion by hyperpolarizing the membrane potential and reducing Ca(2+) entry

nork Zaborska, Karolina E., Dadi, Prasanna K., Dickerson, Matthew T., Nakhe, Arya Y., Thorson, Ariel S., Schaub, Charles M., Graff, Sarah M., Stanley, Jade E., Kondapavuluru, Roy S., Denton, Jerod S., Jacobson, David A.
Argitaratua izan da Mol Metab (2020)

G6PC2: A Negative Regulator of Basal Glucose-Stimulated Insulin Secretion

nork Pound, Lynley D., Oeser, James K., O’Brien, Tracy P., Wang, Yingda, Faulman, Chandler J., Dadi, Prasanna K., Jacobson, David A., Hutton, John C., McGuinness, Owen P., Shiota, Masakazu, O’Brien, Richard M.
Argitaratua 2013

Neurog3-independent methylation is the earliest detectable mark distinguishing pancreatic progenitor identity

nork Liu, Jing, Banerjee, Amrita, Herring, Charles A., Attalla, Jonathan, Hu, Ruiying, Xu, Yanwen, Shao, Qiujia, Simmons, Alan J., Dadi, Prasanna K., Wang, Sui, Jacobson, David A., Liu, Bindong, Hodges, Emily, Lau, Ken S., Gu, Guoqiang
Argitaratua izan da Dev Cell (2019)