Direct Activation of β-Cell K(ATP) Channels with a Novel Xanthine Derivative

ATP-regulated potassium (K(ATP)) channel complexes of inward rectifier potassium channel (K(ir)) 6.2 and sulfonylurea receptor (SUR) 1 critically regulate pancreatic islet β-cell membrane potential, calcium influx, and insulin secretion, and consequently, represent important drug targets for metabol...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Raphemot, Rene, Swale, Daniel R., Dadi, Prasanna K., Jacobson, David A., Cooper, Paige, Wojtovich, Andrew P., Banerjee, Sreedatta, Nichols, Colin G., Denton, Jerod S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014665/
https://ncbi.nlm.nih.gov/pubmed/24646456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.091884
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados