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Direct Activation of β-Cell K(ATP) Channels with a Novel Xanthine Derivative
ATP-regulated potassium (K(ATP)) channel complexes of inward rectifier potassium channel (K(ir)) 6.2 and sulfonylurea receptor (SUR) 1 critically regulate pancreatic islet β-cell membrane potential, calcium influx, and insulin secretion, and consequently, represent important drug targets for metabol...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4014665/ https://ncbi.nlm.nih.gov/pubmed/24646456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.091884 |
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