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The shifting landscape of K(ATP) channelopathies and the need for ‘sharper’ therapeutics
ATP-sensitive potassium (K(ATP)) channels play fundamental roles in the regulation of endocrine, neural and cardiovascular function. Small-molecule inhibitors (e.g., sulfonylurea drugs) or activators (e.g., diazoxide) acting on SUR1 or SUR2 have been used clinically for decades to manage the inappro...
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| Udgivet i: | Future Med Chem |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Future Science Ltd
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4976861/ https://ncbi.nlm.nih.gov/pubmed/27161588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2016-0005 |
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