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The shifting landscape of K(ATP) channelopathies and the need for ‘sharper’ therapeutics

ATP-sensitive potassium (K(ATP)) channels play fundamental roles in the regulation of endocrine, neural and cardiovascular function. Small-molecule inhibitors (e.g., sulfonylurea drugs) or activators (e.g., diazoxide) acting on SUR1 or SUR2 have been used clinically for decades to manage the inappro...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Future Med Chem
Egile Nagusiak: Kharade, Sujay V, Nichols, Colin, Denton, Jerod S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Future Science Ltd 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976861/
https://ncbi.nlm.nih.gov/pubmed/27161588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2016-0005
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