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Neurog3-independent methylation is the earliest detectable mark distinguishing pancreatic progenitor identity
In the developing pancreas, transient Neurog3-expressing progenitors give rise to four major islet-cell types, α, β, δ, and γ; when and how the Neurog3(+) cells choose cell-fate is unknown. Using single-cell RNAseq, trajectory analysis, and combinatorial lineage tracing, we showed here that the Neur...
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| Publicado no: | Dev Cell |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6327977/ https://ncbi.nlm.nih.gov/pubmed/30620902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.11.048 |
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