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Cre reconstitution allows for DNA recombination selectively in dual-marker-expressing cells in transgenic mice
Cre/LoxP-based DNA recombination has been used to introduce desired DNA rearrangements in various organisms, having for example, greatly assisted genetic analyses in mice. For most applications, single gene promoters are used to drive Cre production for conditional gene activation/inactivation or li...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2095822/ https://ncbi.nlm.nih.gov/pubmed/17893102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm559 |
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