Dual Fluorescent Reporter Pig for Cre Recombination: Transgene Placement at the ROSA26 Locus

We are extending the Cre/loxP site-specific recombination system to pigs, focussing on conditional and tissue-specific expression of oncogenic mutations to model human cancers. Identifying the location, pattern and extent of Cre recombination in vivo is an important aspect of this technology. Here w...

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Autors principals: Li, Shun, Flisikowska, Tatiana, Kurome, Mayuko, Zakhartchenko, Valeri, Kessler, Barbara, Saur, Dieter, Kind, Alexander, Wolf, Eckhard, Flisikowski, Krzysztof, Schnieke, Angelika
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099177/
https://ncbi.nlm.nih.gov/pubmed/25025770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102455
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