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Dual Fluorescent Reporter Pig for Cre Recombination: Transgene Placement at the ROSA26 Locus
We are extending the Cre/loxP site-specific recombination system to pigs, focussing on conditional and tissue-specific expression of oncogenic mutations to model human cancers. Identifying the location, pattern and extent of Cre recombination in vivo is an important aspect of this technology. Here w...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4099177/ https://ncbi.nlm.nih.gov/pubmed/25025770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102455 |
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