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The Pancreatic Islet Beta Cell-Enriched Transcription Factor Pdx-1 Regulates Slc30a8 Gene Transcription Through an Intronic Enhancer
The SLC30A8 gene encodes the zinc transporter ZnT-8, which provides zinc for insulin-hexamer formation. Genome-wide association studies have shown that a polymorphic variant in SLC30A8 is associated with altered susceptibility to type 2 diabetes and we recently reported that glucose-stimulated insul...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4130494/ https://ncbi.nlm.nih.gov/pubmed/20942803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101488 |
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