Deletion of the G6pc2 Gene Encoding the Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein Does Not Affect the Progression or Incidence of Type 1 Diabetes in NOD/ShiLtJ Mice

OBJECTIVE: Islet-specific glucose-6-phosphatase catalytic subunit–related protein (IGRP), now known as G6PC2, is a major target of autoreactive T cells implicated in the pathogenesis of type 1 diabetes in both mice and humans. This study aimed to determine whether suppression of G6p2 gene expression...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Oeser, James K., Parekh, Vrajesh V., Wang, Yingda, Jegadeesh, Naresh K., Sarkar, Suparna A., Wong, Randall, Lee, Catherine E., Pound, Lynley D., Hutton, John C., Van Kaer, Luc, O’Brien, Richard M.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2011
Fag:
Immunology and Transplantation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198073/
https://ncbi.nlm.nih.gov/pubmed/21896930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0220
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker