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Defective Glycogenesis Contributes Toward the Inability to Suppress Hepatic Glucose Production in Response to Hyperglycemia and Hyperinsulinemia in Zucker Diabetic Fatty Rats

OBJECTIVE: Examine whether normalizing net hepatic glycogenesis restores endogenous glucose production and hepatic glucose phosphorylation in response to diabetic levels of plasma glucose and insulin in Zucker diabetic fatty rats (ZDF). RESEARCH DESIGN AND METHODS: Hepatic glucose and intermediate f...

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主要な著者: Torres, Tracy P., Fujimoto, Yuka, Donahue, E.P., Printz, Richard L., Houseknecht, Karen L., Treadway, Judith L., Shiota, Masakazu
フォーマット: Artigo
言語:Inglês
出版事項: American Diabetes Association 2011
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161317/
https://ncbi.nlm.nih.gov/pubmed/21771972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1156
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