Defective Glycogenesis Contributes Toward the Inability to Suppress Hepatic Glucose Production in Response to Hyperglycemia and Hyperinsulinemia in Zucker Diabetic Fatty Rats

OBJECTIVE: Examine whether normalizing net hepatic glycogenesis restores endogenous glucose production and hepatic glucose phosphorylation in response to diabetic levels of plasma glucose and insulin in Zucker diabetic fatty rats (ZDF). RESEARCH DESIGN AND METHODS: Hepatic glucose and intermediate f...

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Main Authors: Torres, Tracy P., Fujimoto, Yuka, Donahue, E.P., Printz, Richard L., Houseknecht, Karen L., Treadway, Judith L., Shiota, Masakazu
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2011
Teme:
Metabolism
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161317/
https://ncbi.nlm.nih.gov/pubmed/21771972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1156
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