Morning Hyperinsulinemia Primes the Liver for Glucose Uptake and Glycogen Storage Later in the Day

We observed that a 4-h morning (AM) duodenal infusion of glucose versus saline doubled hepatic glucose uptake (HGU) and storage during a hyperinsulinemic–hyperglycemic (HIHG) clamp that afternoon (PM). To separate the effects of AM hyperglycemia versus AM hyperinsulinemia on the PM response, we used...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Moore, Mary Courtney, Smith, Marta S., Farmer, Ben, Coate, Katie C., Kraft, Guillaume, Shiota, Masakazu, Williams, Phillip E., Cherrington, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2018
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014555/
https://ncbi.nlm.nih.gov/pubmed/29666062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-0979
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