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Pyruvate and Metabolic Flexibility: Illuminating a path toward selective cancer therapies

Dysregulated metabolism is an emerging hallmark of cancer and there is abundant interest in developing therapies to selectively target these aberrant metabolic phenotypes. Sitting at the decision point between mitochondrial carbohydrate oxidation and aerobic glycolysis (i.e., the “Warburg Effect”),...

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Detalhes bibliográficos
Publicado no:Trends Biochem Sci
Main Authors: Olson, Kristofor A., Schell, John C., Rutter, Jared
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783264/
https://ncbi.nlm.nih.gov/pubmed/26873641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2016.01.002
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