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Pyruvate and Metabolic Flexibility: Illuminating a path toward selective cancer therapies
Dysregulated metabolism is an emerging hallmark of cancer and there is abundant interest in developing therapies to selectively target these aberrant metabolic phenotypes. Sitting at the decision point between mitochondrial carbohydrate oxidation and aerobic glycolysis (i.e., the “Warburg Effect”),...
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| Τόπος έκδοσης: | Trends Biochem Sci |
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| Κύριοι συγγραφείς: | , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4783264/ https://ncbi.nlm.nih.gov/pubmed/26873641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2016.01.002 |
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