Identification of lipid-phosphatidylserine (PS) as the target of unbiasedly selected cancer specific peptide-peptoid hybrid PPS1

nork Desai, Tanvi J., Toombs, Jason E., Minna, John D., Brekken, Rolf A., Udugamasooriya, Damith Gomika
Argitaratua izan da Oncotarget (2016)

Smac mimetic-derived augmentation of chemotherapeutic response in experimental pancreatic cancer

nork Awasthi, Niranjan, Kirane, Amanda, Schwarz, Margaret A, Toombs, Jason E, Brekken, Rolf A, Schwarz, Roderich E
Argitaratua 2011

Cytokine Levels Correlate with Immune Cell Infiltration after Anti-VEGF Therapy in Preclinical Mouse Models of Breast Cancer

nork Roland, Christina L., Lynn, Kristi D., Toombs, Jason E., Dineen, Sean P., Udugamasooriya, D. Gomika, Brekken, Rolf A.
Argitaratua 2009

Losartan Slows Pancreatic Tumor Progression and Extends Survival of SPARC-Null Mice by Abrogating Aberrant TGFβ Activation

nork Arnold, Shanna A., Rivera, Lee B., Carbon, Juliet G., Toombs, Jason E., Chang, Chi-Lun, Bradshaw, Amy D., Brekken, Rolf A.
Argitaratua 2012

Epithelial–mesenchymal transition increases tumor sensitivity to COX-2 inhibition by apricoxib

nork Kirane, Amanda, Toombs, Jason E, Larsen, Jill E, Ostapoff, Katherine T, Meshaw, Kathryn R, Zaknoen, Sara, Brekken, Rolf A, Burrows, Francis J
Argitaratua 2012

Tris DBA palladium is highly effective against growth and metastasis of pancreatic cancer in an orthotopic model

nork Díaz, Begoña, Ostapoff, Katherine T., Toombs, Jason E., Lo, Jason, Bonner, Michael Y., Curatolo, Adam, Adsay, Volkan, Brekken, Rolf A., Arbiser, Jack L.
Argitaratua izan da Oncotarget (2016)

Apricoxib, a Novel Inhibitor of COX-2, Markedly Improves Standard Therapy Response in Molecularly Defined Models of Pancreatic Cancer

nork Kirane, Amanda, Toombs, Jason E., Ostapoff, Katherine, Carbon, Juliet G., Zaknoen, Sara, Braunfeld, Jordan, Schwarz, Roderich E., Burrows, Francis J., Brekken, Rolf A.
Argitaratua 2012

Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation

nork Stefanius, Karoliina, Servage, Kelly, de Souza Santos, Marcela, Gray, Hillery Fields, Toombs, Jason E, Chimalapati, Suneeta, Kim, Min S, Malladi, Venkat S, Brekken, Rolf, Orth, Kim
Argitaratua izan da eLife (2019)

r84, a Novel Therapeutic Antibody against Mouse and Human VEGF with Potent Anti-Tumor Activity and Limited Toxicity Induction

nork Sullivan, Laura A., Carbon, Juliet G., Roland, Christina L., Toombs, Jason E., Nyquist-Andersen, Mari, Kavlie, Anita, Schlunegger, Kyle, Richardson, James A., Brekken, Rolf A.
Argitaratua 2010

Stromal platelet-derived growth factor receptor α (PDGFRα) provides a therapeutic target independent of tumor cell PDGFRα expression in lung cancer xenografts

nork Gerber, David E., Gupta, Puja, Dellinger, Michael T., Toombs, Jason E., Peyton, Michael, Duignan, Inga, Malaby, Jennifer, Bailey, Timothy, Burns, Colleen, Brekken, Rolf A., Loizos, Nick
Argitaratua 2012

Collagen signaling enhances tumor progression after anti-VEGF therapy in a murine model of pancreatic ductal adenocarcinoma

nork Aguilera, Kristina Y., Rivera, Lee B., Hur, Hoon, Carbon, Juliet G., Toombs, Jason E., Goldstein, Courtney D., Dellinger, Michael T., Castrillon, Diego H., Brekken, Rolf A.
Argitaratua 2013

Smac mimetic increases chemotherapy response and improves survival in mice with pancreatic cancer

nork Dineen, Sean P., Roland, Christina L., Greer, Rachel, Carbon, Juliet G., Toombs, Jason E., Gupta, Puja, Bardeesy, Nabeel, Sun, Haizhou, Williams, Noelle, Minna, John D., Brekken, Rolf A.
Argitaratua 2010

Fibulin-5 blocks microenvironmental ROS in pancreatic cancer

nork Wang, Miao, Topalovski, Mary, Toombs, Jason E., Wright, Christopher M., Moore, Zachary R., Boothman, David A., Yanagisawa, Hiromi, Wang, Huamin, Witkiewicz, Agnieszka, Castrillon, Diego H., Brekken, Rolf A.
Argitaratua izan da Cancer Res (2015)

Warfarin blocks Gas6-mediated Axl activation required for pancreatic cancer epithelial plasticity and metastasis

nork Kirane, Amanda, Ludwig, Kathleen F., Sorrelle, Noah, Haaland, Gry, Sandal, Tone, Ranaweera, Renate, Toombs, Jason E., Wang, Miao, Dineen, Sean P., Micklem, David, Dellinger, Michael T., Lorens, James B., Brekken, Rolf A.
Argitaratua izan da Cancer Res (2015)

Mode of action and pharmacogenomic biomarkers for exceptional responders to didemnin B

nork Potts, Malia B., McMillan, Elizabeth A., Rosales, Tracy I., Kim, Hyun Seok, Ou, Yi-Hung, Toombs, Jason E., Brekken, Rolf A., Minden, Mark D., MacMillan, John B., White, Michael A.
Argitaratua izan da Nat Chem Biol (2015)

Small molecule inhibition of Axl targets tumor immune suppression and enhances chemotherapy in pancreatic cancer

nork Ludwig, Kathleen F., Du, Wenting, Sorrelle, Noah B., Wnuk-Lipinska, Katarzyna, Topalovski, Mary, Toombs, Jason E., Cruz, Victoria H., Yabuuchi, Shinichi, Rajeshkumar, N.V., Maitra, Anirban, Lorens, James B., Brekken, Rolf A.
Argitaratua izan da Cancer Res (2017)

Hemolysis-associated phosphatidylserine exposure promotes polyclonal plasmablast differentiation

nork Vijay, Rahul, Guthmiller, Jenna J., Sturtz, Alexandria J., Crooks, Sequoia, Johnson, Jordan T., Li, Lei, Lan, Linda Yu-Ling, Pope, Rosemary L., Chen, Yani, Rogers, Kai J., Dutta, Nirmal, Toombs, Jason E., Wilson, Mary E., Wilson, Patrick C., Maury, Wendy, Brekken, Rolf A., Butler, Noah S.
Argitaratua izan da J Exp Med (2021)

Systematic Identification of Molecular Subtype-Selective Vulnerabilities in Non Small Cell Lung Cancer

nork Kim, Hyun Seok, Mendiratta, Saurabh, Kim, Jiyeon, Pecot, Chad Victor, Larsen, Jill E., Zubovych, Iryna, Seo, Bo Yeun, Kim, Jimi, Eskiocak, Banu, Chung, Hannah, McMillan, Elizabeth, Wu, Sherry, De Brabander, Jef, Komurov, Kakajan, Toombs, Jason E., Wei, Shuguang, Peyton, Michael, Williams, Noelle, Gazdar, Adi F., Posner, Bruce A., Brekken, Rolf, Sood, Anil K., Deberardinis, Ralph J., Roth, Michael G., Minna, John D., White, Michael A.
Argitaratua 2013