Fibulin-5 blocks microenvironmental ROS in pancreatic cancer

Elevated oxidative stress is an aberration seen in many solid tumors, and exploiting this biochemical difference has the potential to enhance the efficacy of anti-cancer agents. Homeostasis of reactive oxygen species (ROS) is important for normal cell function, but excessive production of ROS can re...

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Publicat a:Cancer Res
Autors principals: Wang, Miao, Topalovski, Mary, Toombs, Jason E., Wright, Christopher M., Moore, Zachary R., Boothman, David A., Yanagisawa, Hiromi, Wang, Huamin, Witkiewicz, Agnieszka, Castrillon, Diego H., Brekken, Rolf A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668215/
https://ncbi.nlm.nih.gov/pubmed/26577699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0744
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