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Fibulin-5 blocks microenvironmental ROS in pancreatic cancer

Elevated oxidative stress is an aberration seen in many solid tumors, and exploiting this biochemical difference has the potential to enhance the efficacy of anti-cancer agents. Homeostasis of reactive oxygen species (ROS) is important for normal cell function, but excessive production of ROS can re...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Wang, Miao, Topalovski, Mary, Toombs, Jason E., Wright, Christopher M., Moore, Zachary R., Boothman, David A., Yanagisawa, Hiromi, Wang, Huamin, Witkiewicz, Agnieszka, Castrillon, Diego H., Brekken, Rolf A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668215/
https://ncbi.nlm.nih.gov/pubmed/26577699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0744
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