Collagen signaling enhances tumor progression after anti-VEGF therapy in a murine model of pancreatic ductal adenocarcinoma

There is growing evidence that anti-angiogenic therapy stimulates cancer cell invasion and metastasis. However, the underlying molecular mechanisms responsible for these changes have not been fully defined. Here we report that anti-VEGF therapy promotes local invasion and metastasis by inducing coll...

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Detalhes bibliográficos
Main Authors: Aguilera, Kristina Y., Rivera, Lee B., Hur, Hoon, Carbon, Juliet G., Toombs, Jason E., Goldstein, Courtney D., Dellinger, Michael T., Castrillon, Diego H., Brekken, Rolf A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944405/
https://ncbi.nlm.nih.gov/pubmed/24346431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2800
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