Molecular Biology of Lung Cancer: Clinical Implications

Por Larsen, Jill E., Minna, John D.
Publicado em 2011

Targeted Therapies for Lung Cancer: Clinical Experience and Novel Agents

Por Larsen, Jill E., Cascone, Tina, Gerber, David E., Heymach, John V., Minna, John D.
Publicado em 2011

Epithelial–mesenchymal transition increases tumor sensitivity to COX-2 inhibition by apricoxib

Por Kirane, Amanda, Toombs, Jason E, Larsen, Jill E, Ostapoff, Katherine T, Meshaw, Kathryn R, Zaknoen, Sara, Brekken, Rolf A, Burrows, Francis J
Publicado em 2012

Expression profiling identifies genes involved in emphysema severity

Por Francis, Santiyagu M Savarimuthu, Larsen, Jill E, Pavey, Sandra J, Bowman, Rayleen V, Hayward, Nicholas K, Fong, Kwun M, Yang, Ian A
Publicado em 2009

Pax gene diversity in the basal cnidarian Acropora millepora (Cnidaria, Anthozoa): Implications for the evolution of the Pax gene family

Por Miller, David J., Hayward, David C., Reece-Hoyes, John S., Scholten, Ingo, Catmull, Julian, Gehring, Walter J., Callaerts, Patrick, Larsen, Jill E., Ball, Eldon E.
Publicado em 2000

Nuclear Receptor Expression and Function in Human Lung Cancer Pathogenesis

Por Kim, Jihye, Sato, Mitsuo, Choi, Jong-Whan, Kim, Hyun-Won, Yeh, Byung-Il, Larsen, Jill E., Minna, John D., Cha, Jeong-Heon, Jeong, Yangsik
Publicado no PLoS One (2015)

SMAC mimetic (JP1201) sensitizes non-small cell lung cancers to multiple chemotherapy agents in an IAP dependent but TNFα independent manner

Por Greer, Rachel M., Peyton, Michael, Larsen, Jill E., Girard, Luc, Xie, Yang, Gazdar, Adi, Harran, Patrick, Wang, Lai, Brekken, Rolf A., Wang, Xiaodong, Minna, John D.
Publicado em 2011

MicroRNA-218 Is Deleted and Downregulated in Lung Squamous Cell Carcinoma

Por Davidson, Morgan R., Larsen, Jill E., Yang, Ian A., Hayward, Nicholas K., Clarke, Belinda E., Duhig, Edwina E., Passmore, Linda H., Bowman, Rayleen V., Fong, Kwun M.
Publicado em 2010

Genes and Gene Ontologies Common to Airflow Obstruction and Emphysema in the Lungs of Patients with COPD

Por Savarimuthu Francis, Santiyagu M., Larsen, Jill E., Pavey, Sandra J., Duhig, Edwina E., Clarke, Belinda E., Bowman, Rayleen V., Hayward, Nick K., Fong, Kwun M., Yang, Ian A.
Publicado em 2011

Loss of miR-125a expression in a model of K-ras-dependent pulmonary premalignancy

Por Liclican, Elvira L., Walser, Tonya C., Hazra, Saswati, Krysan, Kostyantyn, Park, Stacy J., Pagano, Paul C., Gardner, Brian K., Larsen, Jill E., Minna, John D., Dubinett, Steven M.
Publicado em 2014

NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM

Por Osborne, Jihan K., Larsen, Jill E., Shields, Misty D., Gonzales, Joshua X., Shames, David S., Sato, Mitsuo, Kulkarni, Ashwinikumar, Wistuba, Ignacio I., Girard, Luc, Minna, John D., Cobb, Melanie H.
Publicado em 2013

Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells

Por Zaganjor, Elma, Osborne, Jihan K., Weil, Lauren M., Diaz-Martinez, Laura A., Gonzales, Joshua X., Singel, Stina M., Larsen, Jill E., Girard, Luc, Minna, John D., Cobb, Melanie H.
Publicado em 2013

Knockdown of Oncogenic KRAS in Non-Small Cell Lung Cancers Suppresses Tumor Growth and Sensitizes Tumor Cells to Targeted Therapy

Por Sunaga, Noriaki, Shames, David S., Girard, Luc, Peyton, Michael, Larsen, Jill E., Imai, Hisao, Soh, Junichi, Sato, Mitsuo, Yanagitani, Noriko, Kaira, Kyoichi, Xie, Yang, Gazdar, Adi F., Mori, Masatomo, Minna, John D.
Publicado em 2011

Array-Comparative Genomic Hybridization Reveals Loss of SOCS6 Is Associated with Poor Prognosis in Primary Lung Squamous Cell Carcinoma

Por Sriram, Krishna B., Larsen, Jill E., Savarimuthu Francis, Santiyagu M., Wright, Casey M., Clarke, Belinda E., Duhig, Edwina E., Brown, Kevin M., Hayward, Nicholas K., Yang, Ian A., Bowman, Rayleen V., Fong, Kwun M.
Publicado em 2012

Systematic siRNA Screen Unmasks NSCLC Growth Dependence by Palmitoyltransferase DHHC5

Por Tian, Hui, Lu, Jui-Yun, Shao, Chunli, Huffman, Kenneth E., Carstens, Ryan M., Larsen, Jill E., Girard, Luc, Liu, Hui, Rodriguez-Canales, Jaime, Frenkel, Eugene P., Wistuba, Ignacio I., Minna, John D., Hofmann, Sandra L.
Publicado no Mol Cancer Res (2015)

Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations

Por Sato, Mitsuo, Larsen, Jill E., Lee, Woochang, Sun, Han, Shames, David S., Dalvi, Maithili P., Ramirez, Ruben D., Tang, Hao, DiMaio, J. Michael, Gao, Boning, Xie, Yang, Wistuba, Ignacio I., Gazdar, Adi F., Shay, Jerry W., Minna, John D.
Publicado em 2013

ZEB1 drives epithelial-to-mesenchymal transition in lung cancer

Por Larsen, Jill E., Nathan, Vaishnavi, Osborne, Jihan K., Farrow, Rebecca K., Deb, Dhruba, Sullivan, James P., Dospoy, Patrick D., Augustyn, Alexander, Hight, Suzie K., Sato, Mitsuo, Girard, Luc, Behrens, Carmen, Wistuba, Ignacio I., Gazdar, Adi F., Hayward, Nicholas K., Minna, John D.
Publicado no J Clin Invest (2016)

ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers

Por Augustyn, Alexander, Borromeo, Mark, Wang, Tao, Fujimoto, Junya, Shao, Chunli, Dospoy, Patrick D., Lee, Victoria, Tan, Christopher, Sullivan, James P., Larsen, Jill E., Girard, Luc, Behrens, Carmen, Wistuba, Ignacio I., Xie, Yang, Cobb, Melanie H., Gazdar, Adi F., Johnson, Jane E., Minna, John D.
Publicado em 2014

Validations of SCT Methylation as a Hallmark Biomarker for Lung Cancers

Por Zhang, Yu-An, Ma, Xiaotu, Sathe, Adwait, Fujimoto, Junya, Wistuba, Ignacio, Lam, Stephen, Yatabe, Yasushi, Wang, Yi-Wei, Stastny, Victor, Gao, Boning, Larsen, Jill E, Girard, Luc, Liu, Xiaoyun, Song, Kai, Behrens, Carmen, Kalhor, Neda, Xie, Yang, Zhang, Michael Q, Minna, John D, Gazdar, Adi F
Publicado no J Thorac Oncol (2015)

Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on Notch signaling

Por Sullivan, James P., Spinola, Monica, Dodge, Michael, Raso, Maria G., Behrens, Carmen, Gao, Boning, Schuster, Katja, Shao, Chunli, Larsen, Jill E., Sullivan, Laura A., Honorio, Sofia, Xie, Yang, Scaglioni, Pier P., DiMaio, J. Michael, Gazdar, Adi F., Shay, Jerry W., Wistuba, Ignacio I., Minna, John D.
Publicado em 2010