ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers

Aggressive neuroendocrine lung cancers, including small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC), represent an understudied tumor subset that accounts for approximately 40,000 new lung cancer cases per year in the United States. No targeted therapy exists for these tumors. We d...

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Autors principals: Augustyn, Alexander, Borromeo, Mark, Wang, Tao, Fujimoto, Junya, Shao, Chunli, Dospoy, Patrick D., Lee, Victoria, Tan, Christopher, Sullivan, James P., Larsen, Jill E., Girard, Luc, Behrens, Carmen, Wistuba, Ignacio I., Xie, Yang, Cobb, Melanie H., Gazdar, Adi F., Johnson, Jane E., Minna, John D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205603/
https://ncbi.nlm.nih.gov/pubmed/25267614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410419111
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