NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM

Small-cell lung cancer and other aggressive neuroendocrine cancers are often associated with early dissemination and frequent metastases. We demonstrate that neurogenic differentiation 1 (NeuroD1) is a regulatory hub securing cross talk among survival and migratory-inducing signaling pathways in neu...

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Detalhes bibliográficos
Main Authors: Osborne, Jihan K., Larsen, Jill E., Shields, Misty D., Gonzales, Joshua X., Shames, David S., Sato, Mitsuo, Kulkarni, Ashwinikumar, Wistuba, Ignacio I., Girard, Luc, Minna, John D., Cobb, Melanie H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631659/
https://ncbi.nlm.nih.gov/pubmed/23553831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303932110
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