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NeuroD1 mediates nicotine-induced migration and invasion via regulation of the nicotinic acetylcholine receptor subunits in a subset of neural and neuroendocrine carcinomas

Cigarette smoking is a major risk factor for acquisition of small cell lung cancer (SCLC). A role has been demonstrated for the basic helix-loop-helix transcription factor NeuroD1 in the pathogenesis of neural and neuroendocrine lung cancer, including SCLC. In the present study we investigate the po...

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Detalhes bibliográficos
Main Authors: Osborne, Jihan K., Guerra, Marcy L., Gonzales, Joshua X., McMillan, Elizabeth A., Minna, John D., Cobb, Melanie H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038504/
https://ncbi.nlm.nih.gov/pubmed/24719457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-06-0316
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