Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on Notch signaling

Aldehyde dehydrogenase (ALDH) is a candidate marker for lung cancer cells with stem cell-like properties. Immunohistochemical staining of a large panel of primary non-small cell lung cancer (NSCLC) samples for the ALDH1A1, ALDH3A1 and CD133 revealed a significant correlation between ALDH1A1 (but not...

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Autors principals: Sullivan, James P., Spinola, Monica, Dodge, Michael, Raso, Maria G., Behrens, Carmen, Gao, Boning, Schuster, Katja, Shao, Chunli, Larsen, Jill E., Sullivan, Laura A., Honorio, Sofia, Xie, Yang, Scaglioni, Pier P., DiMaio, J. Michael, Gazdar, Adi F., Shay, Jerry W., Wistuba, Ignacio I., Minna, John D.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058307/
https://ncbi.nlm.nih.gov/pubmed/21118965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0881
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