Lung Cancer and Immunity Markers

por Lim, Raymond J., Liu, Bin, Krysan, Kostyantyn, Dubinett, Steven M.
Publicado en Cancer Epidemiol Biomarkers Prev (2020)

Autocrine/Paracrine Prostaglandin E2 Production by Non-small Cell Lung Cancer Cells Regulates Matrix Metalloproteinase-2 and CD44 in Cyclooxygenase-2-dependent Invasion

por Dohadwala, Mariam, Batra, Raj K., Luo, Jie, Lin, Ying, Krysan, Kostyantyn, Põld, Mehis, Sharma, Sherven, Dubinett, Steven M.
Publicado 2002

The Inflammatory Tumor Microenvironment, Epithelial Mesenchymal Transition and Lung Carcinogenesis

por Heinrich, Eileen L., Walser, Tonya C., Krysan, Kostyantyn, Liclican, Elvira L., Grant, Jeanette L., Rodriguez, Nicole L., Dubinett, Steven M.
Publicado 2011

Elevated levels of CXC chemokine connective tissue activating peptide (CTAP)-III in lung cancer patients

por Lee, Gina, Gardner, Brian K, Elashoff, David A, Purcell, Colleen M, Sandha, Harpavan S, Mao, Jenny T, Krysan, Kostyantyn, Lee, Jay M, Dubinett, Steven M
Publicado 2011

A novel molecular pathway for Snail-dependent, SPARC-mediated invasion in non-small cell lung cancer pathogenesis

por Grant, Jeanette L., Fishbein, Michael C., Hong, Long-Sheng, Krysan, Kostyantyn, Minna, John D., Shay, Jerry W., Walser, Tonya C., Dubinett, Steven M.
Publicado 2013

Loss of miR-125a expression in a model of K-ras-dependent pulmonary premalignancy

por Liclican, Elvira L., Walser, Tonya C., Hazra, Saswati, Krysan, Kostyantyn, Park, Stacy J., Pagano, Paul C., Gardner, Brian K., Larsen, Jill E., Minna, John D., Dubinett, Steven M.
Publicado 2014

Combination Treatment with Apricoxib and IL-27 Enhances Inhibition of Epithelial-Mesenchymal Transition in Human Lung Cancer Cells through a STAT1 Dominant Pathway

por Lee, Mi-Heon, Kachroo, Puja, Pagano, Paul C, Yanagawa, Jane, Wang, Gerald, Walser, Tonya C, Krysan, Kostyantyn, Sharma, Sherven, John, Maie St., Dubinett, Steven M, Lee, Jay M
Publicado en J Cancer Sci Ther (2014)

IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer

por Kachroo, Puja, Lee, Mi-Heon, Zhang, Ling, Baratelli, Felicita, Lee, Gina, Srivastava, Minu K, Wang, Gerald, Walser, Tonya C, Krysan, Kostyantyn, Sharma, Sherven, Dubinett, Steven M, Lee, Jay M
Publicado 2013

PGE2-driven Expression of c-Myc and OncomiR-17-92 Contributes to Apoptosis Resistance in NSCLC

por Krysan, Kostyantyn, Kusko, Rebecca, Grogan, Tristan, O'Hearn, James, Reckamp, Karen L., Walser, Tonya C., Garon, Edward B., Lenburg, Marc E., Sharma, Sherven, Spira, Avrum E., Elashoff, David, Dubinett, Steven M.
Publicado 2014

CancerLocator: non-invasive cancer diagnosis and tissue-of-origin prediction using methylation profiles of cell-free DNA

por Kang, Shuli, Li, Qingjiao, Chen, Quan, Zhou, Yonggang, Park, Stacy, Lee, Gina, Grimes, Brandon, Krysan, Kostyantyn, Yu, Min, Wang, Wei, Alber, Frank, Sun, Fengzhu, Dubinett, Steven M., Li, Wenyuan, Zhou, Xianghong Jasmine
Publicado en Genome Biol (2017)

Increased PD-L1 expression in KRAS mutated premalignant human bronchial epithelial cells is enhanced by LKB1 loss and mediated by ERK activation

por Lee, Mi-Heon, Yanagawa, Jane, Li, Rui, Walser, Tonya C, Krysan, Kostyantyn, Wang, Gerald, Goldman, Jonathan W, Garon, Edward B Garon, Zeng, Gang, Sharma, Sherven, Minna, John D, Carbone, David, Dubinett, Steven M, Lee, Jay M
Publicado en J Immunother Cancer (2015)

Novel Kras-mutant murine models of non-small cell lung cancer possessing co-occurring oncogenic mutations and increased tumor mutational burden

por Salehi-Rad, Ramin, Li, Rui, Tran, Linh M., Lim, Raymond J., Abascal, Jensen, Momcilovic, Milica, Park, Stacy J., Ong, Stephanie L., Shabihkhani, Maryam, Huang, Zi Ling, Paul, Manash, Shackelford, David B., Krysan, Kostyantyn, Liu, Bin, Dubinett, Steven M.
Publicado en Cancer Immunol Immunother (2021)

FRA1 contributes to MEK-ERK pathway-dependent PD-L1 upregulation by KRAS mutation in premalignant human bronchial epithelial cells

por Lee, Mi-Heon, Yanagawa, Jane, Tran, Linh, Walser, Tonya C, Bisht, Bharti, Fung, Eileen, Park, Stacy J, Zeng, Gang, Krysan, Kostyantyn, Wallace, William D, Paul, Manash K, Girard, Luc, Gao, Boning, Minna, John D, Dubinett, Steven M, Lee, Jay M
Publicado en Am J Transl Res (2020)

Elevated neutrophil gelatinase-associated lipocalin contributes to erlotinib resistance in non-small cell lung cancer

por Krysan, Kostyantyn, Cui, Xiaoyan, Gardner, Brian K, Reckamp, Karen L, Wang, Xiaoyan, Hong, Longsheng, Walser, Tonya C, Rodriguez, Nicole L, Pagano, Paul C, Garon, Edward B, Brothers, John F, Elashoff, David, Lee, Jay M, Spira, Avrum E, Sharma, Sherven, Fishbein, Michael C, Dubinett, Steven M
Publicado 2013

The immune contexture associates with the genomic landscape in lung adenomatous premalignancy

por Krysan, Kostyantyn, Tran, Linh M., Grimes, Brandon S., Fishbein, Gregory A., Seki, Atsuko, Gardner, Brian K., Walser, Tonya C., Salehi-rad, Ramin, Yanagawa, Jane, Lee, Jay M., Sharma, Sherven, Aberle, Denise, Spira, Avrum E., Elashoff, David A., Wallace, William D., Fishbein, Michael C., Dubinett, Steven M.
Publicado en Cancer Res (2019)

Molecular subtyping reveals immune alterations associated with progression of bronchial premalignant lesions

por Beane, Jennifer E., Mazzilli, Sarah A., Campbell, Joshua D., Duclos, Grant, Krysan, Kostyantyn, Moy, Christopher, Perdomo, Catalina, Schaffer, Michael, Liu, Gang, Zhang, Sherry, Liu, Hanqiao, Vick, Jessica, Dhillon, Samjot S., Platero, Suso J., Dubinett, Steven M., Stevenson, Christopher, Reid, Mary E., Lenburg, Marc E., Spira, Avrum E.
Publicado en Nat Commun (2019)

Chronic IL-1β-induced inflammation regulates epithelial-to-mesenchymal transition memory phenotypes via epigenetic modifications in non-small cell lung cancer

por Li, Rui, Ong, Stephanie L., Tran, Linh M., Jing, Zhe, Liu, Bin, Park, Stacy J., Huang, Zi Ling, Walser, Tonya C., Heinrich, Eileen L., Lee, Gina, Salehi-Rad, Ramin, Crosson, William P., Pagano, Paul C., Paul, Manash K., Xu, Shili, Herschman, Harvey, Krysan, Kostyantyn, Dubinett, Steven
Publicado en Sci Rep (2020)

Author Correction: Chronic IL-1β-induced inflammation regulates epithelial-to-mesenchymal transition memory phenotypes via epigenetic modifications in non-small cell lung cancer

por Li, Rui, Ong, Stephanie L., Tran, Linh M., Jing, Zhe, Liu, Bin, Park, Stacy J., Huang, Zi Ling, Walser, Tonya C., Heinrich, Eileen L., Lee, Gina, Salehi-Rad, Ramin, Crosson, William P., Pagano, Paul C., Paul, Manash K., Xu, Shili, Herschman, Harvey, Krysan, Kostyantyn, Dubinett, Steven
Publicado en Sci Rep (2020)

Silencing the Snail-dependent RNA splice regulator ESRP1 drives malignant transformation of human pulmonary epithelial cells

por Walser, Tonya C., Jing, Zhe, Tran, Linh M., Lin, Ying Q., Yakobian, Natalie, Wang, Gerald, Krysan, Kostyantyn, Zhu, Li X., Sharma, Sherven, Lee, Mi-Heon, Belperio, John A., Ooi, Aik T., Gomperts, Brigitte N., Shay, Jerry W., Larsen, Jill E., Minna, John D., Hong, Long-sheng, Fishbein, Michael C., Dubinett, Steven M.
Publicado en Cancer Res (2018)

Targeted inhibition of EGFR and glutaminase induces metabolic crisis in EGFR mutant lung cancer

por Momcilovic, Milica, Bailey, Sean T., Lee, Jason T., Fishbein, Michael C., Magyar, Clara, Braas, Daniel, Graeber, Thomas, Jackson, Nicholas J., Czernin, Johannes, Emberley, Ethan, Gross, Matthew, Janes, Julie, Mackinnon, Andy, Pan, Alison, Rodriguez, Mirna, Works, Melissa, Zhang, Winter, Parlati, Francesco, Demo, Susan, Garon, Edward, Krysan, Kostyantyn, Walser, Tonya C., Dubinett, Steven M., Sadeghi, Saman, Christofk, Heather R., Shackelford, David B.
Publicado en Cell Rep (2017)