लोड हो रहा है...

FRA1 contributes to MEK-ERK pathway-dependent PD-L1 upregulation by KRAS mutation in premalignant human bronchial epithelial cells

Oncogenic KRAS mutations are frequently found in non-small cell lung carcinoma (NSCLC) and cause constitutive activation of the MEK-ERK pathway. Many cancer types have been shown to overexpress PD-L1 to escape immune surveillance. FRA1 is a MEK/ERK-dependent oncogenic transcription factor and a memb...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Am J Transl Res
मुख्य लेखकों: Lee, Mi-Heon, Yanagawa, Jane, Tran, Linh, Walser, Tonya C, Bisht, Bharti, Fung, Eileen, Park, Stacy J, Zeng, Gang, Krysan, Kostyantyn, Wallace, William D, Paul, Manash K, Girard, Luc, Gao, Boning, Minna, John D, Dubinett, Steven M, Lee, Jay M
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: e-Century Publishing Corporation 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061839/
https://ncbi.nlm.nih.gov/pubmed/32194893
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!