PGE2-driven Expression of c-Myc and OncomiR-17-92 Contributes to Apoptosis Resistance in NSCLC

Aberrant expression of miRNAs with oncogenic capacities (oncomiRs) has been described for several different malignancies. The first identified oncomiR, miR-17-92, is frequently overexpressed in a variety of cancers and its targets include the tumor suppressor PTEN. The transcription factor c-Myc (MY...

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Bibliografiset tiedot
Päätekijät: Krysan, Kostyantyn, Kusko, Rebecca, Grogan, Tristan, O'Hearn, James, Reckamp, Karen L., Walser, Tonya C., Garon, Edward B., Lenburg, Marc E., Sharma, Sherven, Spira, Avrum E., Elashoff, David, Dubinett, Steven M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020971/
https://ncbi.nlm.nih.gov/pubmed/24469837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0377
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